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BMJ:继发于西地那非治疗后的视网膜静脉阻塞 -案例报道

2017-03-27 xing.T MedSci原创

没有发现特殊的原因,但进一步的问诊显示该患者经常服用西地那非治疗勃起功能障碍。西地那非已知的副作用是引起视网膜血管阻塞。

患者为一名73岁男性,因其右眼黄斑中有棉絮斑(图1)而就诊。十来天后,该患者发展为视网膜浅层出血,并且被诊断出为右侧视网膜分支静脉阻塞。


图1

该患者视力为6/15,没有糖尿病高血压病史,凝血功能检查结果正常。没有发现特殊的原因,但进一步的问诊显示该患者经常服用西地那非治疗勃起功能障碍。西地那非已知的副作用是引起视网膜血管阻塞。

这个病例中,当医生面对无明显原因的血管性眼睛病变时,了解患者全面的用药史变得尤为重要。

原始出处:

Hussein Almuhtaseb. et al. Branch retinal vein occlusion secondary to sildenafil. BMJ2017;356:j753 doi: 10.1136/bmj.j753  

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    2017-06-02 fusion
  2. [GetPortalCommentsPageByObjectIdResponse(id=1697430, encodeId=56dd169e4308b, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Fri Jun 02 13:06:00 CST 2017, time=2017-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1724435, encodeId=12aa1e2443594, content=<a href='/topic/show?id=78ece8958b2' target=_blank style='color:#2F92EE;'>#继发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78958, encryptionId=78ece8958b2, topicName=继发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=499d33645837, createdName=feifers, createdTime=Sat Dec 30 13:06:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1848276, encodeId=71af18482e627, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Feb 03 18:06:00 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696706, encodeId=97d61696e06ea, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Fri Jul 28 08:06:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269854, encodeId=25a01269854c6, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Wed Mar 29 07:06:00 CST 2017, time=2017-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581618, encodeId=080715816189a, content=<a href='/topic/show?id=0f8e90830d9' target=_blank style='color:#2F92EE;'>#视网膜静脉阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90830, encryptionId=0f8e90830d9, topicName=视网膜静脉阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca5e16842121, createdName=passed water, createdTime=Wed Mar 29 07:06:00 CST 2017, time=2017-03-29, status=1, ipAttribution=)]
    2017-12-30 feifers
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    2018-02-03 gaoxiaoe
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    2017-07-28 tomyang96
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    2017-03-29 zutt
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