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BMJ:适度饮酒或与某些心血管疾病风险降低有关

2017-03-25 佚名 生物探索

适度饮酒到底能否有益健康?关于这方面的研究众说纷纭。近日,一项发表于BMJ上的大型研究表示,中度饮酒与几种类型(但并非全部)的心血管疾病的风险降低相关。与禁酒或酗酒相比,一些研究认为适度饮酒有益健康,并与心血管疾病风险降低有关。在英国,中度饮酒被定义为每周摄入不超过14个单位(112克)的酒精。然而,科学家们对这一观察争议不断,一些专家指出了这个证据的几个缺点。例如,应将非饮酒者与因健康状况停止饮

适度饮酒到底能否有益健康?关于这方面的研究众说纷纭。近日,一项发表于BMJ上的大型研究表示,中度饮酒与几种类型(但并非全部)的血管疾病的风险降低相关。

与禁酒或酗酒相比,一些研究认为适度饮酒有益健康,并与血管疾病风险降低有关。在英国,中度饮酒被定义为每周摄入不超过14个单位(112克)的酒精。然而,科学家们对这一观察争议不断,一些专家指出了这个证据的几个缺点。例如,应将非饮酒者与因健康状况停止饮酒的前饮酒者分开。



因此,剑桥大学和伦敦大学学院的研究人员通过分析193万健康英国成年人的电子健康记录来调查酒精消费与12种心血管疾病之间的关系。

所有参与者在研究开始时都没有心血管疾病,不饮酒者与前饮酒者以及偶尔饮酒者分开,从而使研究更加严谨。

在考虑了几个影响因素之后,研究人员发现,与禁酒者相比,中度饮酒与几种心血管疾病(包括心绞痛,心力衰竭和缺血性卒中)风险更低相关。

然而,作者认为,鼓励人们采取饮酒的方式降低心血管风险并不是一种明智的方法,他们应当选择更加安全有效的方式,例如多多锻炼和戒烟。

与中度饮酒相比,重度饮酒(超过推荐值)表现出一系列疾病风险增加,包括心力衰竭,心跳停搏和缺血性中风,但心肌梗死和稳定型心绞痛风险较低。

这是一项观察性研究,因此不能得出关于因果关系的确切结论。此外,作者指出了可能引入偏差的一些研究条件。

不过,他们表示这是第一次如此大规模的调查饮酒与心血管疾病的关系,他们的研究结果对患者咨询,公共卫生交流和疾病预测工具有一定影响。

在一篇链接的社论中,美国哈佛医学院和约翰霍普金斯公共卫生学院的研究人员表示,这项研究“并没有提供关于适度饮酒和心血管疾病风险之间关联的重要新观点。然而,这项工作为越来越大以及更加复杂的研究奠定了基础,这些研究尝试将大量数据塞入一系列有用,可靠和无偏差的发现中,为公众宣传健康,临床护理并指导未来研究方向。”

原始出处:

Steven Bell, genetic epidemiologist,et al.Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.BMJ 2017; 356 doi: https://doi.org/10.1136/bmj.j909 (Published 22 March 2017)

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    2018-02-20 gaoxiaoe
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    2017-03-26 1e10c84am36(暂无匿称)

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