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Stroke:卒中病因学会改变急性卒中患者的血管内治疗效果

2019-12-23 xing.T MedSci原创

由此可见,这些结果提供了与非心脏栓塞性LVO相比,心脏栓塞性LVO患者接受血管内治疗更有效的证据。

卒中病因会促进血栓的形成。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员假设血管内治疗在心脏栓塞和非心脏栓塞大血管闭塞(LVO)患者中得到不同的疗效。

研究人员比较了来自GSR-ET(德国卒中登记-血管内治疗;n=2589)试验的心脏栓塞性和非心脏栓塞性LVO患者的手术特征、再灌注等级和出院后90天的功能结局。为了确定其与功能结局的关联,研究人员使用有序多变量Logistic回归模型计算校正后的比值比和95%CI,并校正了潜在的基线混杂变量。

与非心脏栓塞性LVO相比,单次血栓切除术后,心脏栓塞性LVO患者的血管内治疗成功再灌注率(85.6% vs. 81.0%;P=0.002)和完全再灌注率(45.7% vs. 38.1%;P<0.001)更高。心脏栓塞性LVO患者出院时(调整后的比值比为1.61 [95%CI为1.37-1.88])和90天(调整后的比值比为1.29 [95%CI为1.09-1.53])具有更好的功能结局。在介导分析中,再灌注解释了病因学对出院时功能结局的影响的47%。

由此可见,这些结果提供了与非心脏栓塞性LVO相比,心脏栓塞性LVO患者接受血管内治疗更有效的证据。

原始出处:

Steffen Tiedt.et al.Stroke Etiology Modifies the Effect of Endovascular Treatment in Acute Stroke.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.028383

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    2019-12-24 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1894140, encodeId=da6918941401c, content=<a href='/topic/show?id=5e456463eee' target=_blank style='color:#2F92EE;'>#治疗效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64637, encryptionId=5e456463eee, topicName=治疗效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373a131, createdName=jxrzshh, createdTime=Wed Jan 29 21:37:00 CST 2020, time=2020-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720321, encodeId=9a981e20321d1, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Tue Feb 04 16:37:00 CST 2020, time=2020-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284464, encodeId=20c9128446450, content=<a href='/topic/show?id=d2155222281' target=_blank style='color:#2F92EE;'>#急性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52222, encryptionId=d2155222281, topicName=急性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Wed Dec 25 13:37:00 CST 2019, time=2019-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619987, encodeId=27bf161998e3d, content=<a href='/topic/show?id=aa653606053' target=_blank style='color:#2F92EE;'>#卒中病因学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36060, encryptionId=aa653606053, topicName=卒中病因学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Wed Dec 25 13:37:00 CST 2019, time=2019-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026519, encodeId=719110265194d, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Dec 24 01:37:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032365, encodeId=313a103236513, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Tue Dec 24 01:37:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046968, encodeId=560a1046968ae, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Dec 24 01:37:00 CST 2019, time=2019-12-24, status=1, ipAttribution=)]
    2019-12-24 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1894140, encodeId=da6918941401c, content=<a href='/topic/show?id=5e456463eee' target=_blank style='color:#2F92EE;'>#治疗效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64637, encryptionId=5e456463eee, topicName=治疗效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373a131, createdName=jxrzshh, createdTime=Wed Jan 29 21:37:00 CST 2020, time=2020-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720321, encodeId=9a981e20321d1, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Tue Feb 04 16:37:00 CST 2020, time=2020-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284464, encodeId=20c9128446450, content=<a href='/topic/show?id=d2155222281' target=_blank style='color:#2F92EE;'>#急性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52222, encryptionId=d2155222281, topicName=急性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Wed Dec 25 13:37:00 CST 2019, time=2019-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619987, encodeId=27bf161998e3d, content=<a href='/topic/show?id=aa653606053' target=_blank style='color:#2F92EE;'>#卒中病因学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36060, encryptionId=aa653606053, topicName=卒中病因学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Wed Dec 25 13:37:00 CST 2019, time=2019-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026519, encodeId=719110265194d, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Dec 24 01:37:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032365, encodeId=313a103236513, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Tue Dec 24 01:37:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046968, encodeId=560a1046968ae, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Dec 24 01:37:00 CST 2019, time=2019-12-24, status=1, ipAttribution=)]
    2019-12-24 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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