Baidu
map

别只关心新型抗肿瘤药物,传统化疗药物也该学学了!

2022-07-12 MedSci原创 MedSci原创

化疗药物的基础知识,你都会了吗?

化疗药物是目前治疗肿瘤的主要药物,其可作用在肿瘤细胞生长繁殖的不同环节上,抑制或杀死肿瘤细胞,对原发或转移肿瘤病灶均有治疗作用。然近年来分子靶向物、免疫治疗药物等各类抗肿瘤药物层出不穷,但是传统化疗药物依旧是临床抗肿瘤治疗的主要选择

 

据化疗药物的化学结构及来源,可以将化疗药物区分为烷化剂、抗代谢类药物、植物类药物、抗生素类药物、激素类药物以及杂类药物在此,小编特别整理了化疗药物的相关知识,接下来就由小编带领大家再重新学习一下化疗药物吧!

 

一、化疗药物分类、作用机制及常见药物

 

 

二、化疗药物临床应用管理

 

  • 化疗药物使用前,应该根据产品需要,完善相关检查,如血常规、肝功能、肾功能等。

     

  • 化疗药物的配置应遵循药品说明书,选择合适溶媒以及合适稀释浓度,如羟喜树碱不宜使用葡萄糖溶液或酸性溶液溶解;吡柔比星、奥沙利铂、脂质体类药物如紫杉醇脂质体、多柔比星脂质体不宜使用生理盐水溶解。

     

  • 根据化疗药物的特性选择合适的保存环境,如顺铂、卡铂、亚叶酸钙、达卡巴嗪、长春新碱、表柔比星、放线菌素D等化疗药物应注意避光保存。

     

  • 化疗药物静脉滴注或注射时应注意滴速和给药时间。如长春瑞滨、长春地辛、米托蒽醌、阿霉素类、尼莫司汀、吉西他滨、环磷酰胺等往往需要快滴;氟尿嘧啶、亚叶酸钙、顺铂、异环磷酰胺、紫杉醇等往往需要慢滴。

     

  • 化疗药物的使用,应该遵循一定的原则进行。如化疗药物联用时,应遵循刺激性原则先使用对血管刺激小的药物,随后使用发疱剂等刺激性大的药物。化疗药物联用时,受药物相互作用影响,应当调整给药顺序,常见化疗药物联用时的给药顺序可见下表(表格内容来源于参考文献[1])。

 

 

三、化疗药物常见不良反应及处理
 
 
四、常见问题及解析
1、化疗药物耐药机制如何?应该怎么处理?
 
答:化疗药物的耐药涉及多药耐药基因、凋亡途径、非编码 RNA、肿瘤微环境等生物进程的改变。化疗后出现耐药可以考虑联合应用血管生成抑制剂、P-糖蛋白抑制剂、miRNA抑制剂、中药等抗耐药治疗药物,除此之外,新辅助化疗或免疫治疗联合化疗等方法也可能有效改善耐药。
 
2、常见化疗方案有哪些?
 
答:FP方案(顺铂+氟尿嘧啶),EP方案(依托泊苷+顺铂),TAC方案(多柔比星+紫杉醇),DCF方案(多西他赛+顺铂+氟尿嘧啶),CHOP方案(环磷酰胺+长春新碱+多柔比星+泼尼松),VCM方案(长春新碱+卡铂+甲氨蝶呤),VDLP方案(长春新碱+柔红霉素+门冬酰胺酶+泼尼松),CMF方案(环磷酰胺+甲氨蝶呤+氟尿嘧啶),IE方案(伊立替康+依托泊苷),VELOX方案(奥沙利铂+卡培他滨),FLOT方案(奥沙利铂+氟尿嘧啶+多西他赛),SOX方案(奥沙利铂+S-1),XELOX方案(奥沙利铂+卡培他滨),mFOLFOX方案(5-氟尿嘧啶+亚叶酸钙+奥沙利铂),FOLFIRI方案(伊立替康+亚叶酸钙+氟尿嘧啶),CapIRI方案(伊立替康+卡培他滨)。
参考文献:
[1] 陈静, 赵德华, 楚明明,等. 静脉用抗肿瘤药物临床应用的药学管理[J]. 肿瘤药学, 2020, 10(3):9.
[2] 药品说明书.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1239156, encodeId=d49b12391563d, content=👏👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33578272224, createdName=ms5000000900062349, createdTime=Tue Aug 16 23:28:25 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446822, encodeId=81f91446822d0, content=<a href='/topic/show?id=94bd830865e' target=_blank style='color:#2F92EE;'>#肿瘤药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83086, encryptionId=94bd830865e, topicName=肿瘤药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKneTxOtx0KRAPibib3sfmib4P2269UG6op6ZN5ZKddPvUibR7RfFob8X6FicRugoeY8Dicy4cibArjj168Q/132, createdBy=c17d5287383, createdName=smartjoy, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506731, encodeId=2ee61506e31cf, content=<a href='/topic/show?id=7b8d3358050' target=_blank style='color:#2F92EE;'>#化疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33580, encryptionId=7b8d3358050, topicName=化疗药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5f629793993, createdName=luwei03, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537770, encodeId=5420153e77012, content=<a href='/topic/show?id=1f9983082fa' target=_blank style='color:#2F92EE;'>#肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83082, encryptionId=1f9983082fa, topicName=肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ed1012894470, createdName=30397608, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581784, encodeId=aa0d1581e84a2, content=<a href='/topic/show?id=0813335e996' target=_blank style='color:#2F92EE;'>#化疗药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33579, encryptionId=0813335e996, topicName=化疗药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=298f16872689, createdName=12498cb5m18暂无昵称, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593741, encodeId=cc201593e4142, content=<a href='/topic/show?id=ff895565586' target=_blank style='color:#2F92EE;'>#抗肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55655, encryptionId=ff895565586, topicName=抗肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5e18156549, createdName=zhu_jun9843, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=)]
    2022-08-16 ms5000000900062349

    👏👏👏

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1239156, encodeId=d49b12391563d, content=👏👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33578272224, createdName=ms5000000900062349, createdTime=Tue Aug 16 23:28:25 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446822, encodeId=81f91446822d0, content=<a href='/topic/show?id=94bd830865e' target=_blank style='color:#2F92EE;'>#肿瘤药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83086, encryptionId=94bd830865e, topicName=肿瘤药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKneTxOtx0KRAPibib3sfmib4P2269UG6op6ZN5ZKddPvUibR7RfFob8X6FicRugoeY8Dicy4cibArjj168Q/132, createdBy=c17d5287383, createdName=smartjoy, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506731, encodeId=2ee61506e31cf, content=<a href='/topic/show?id=7b8d3358050' target=_blank style='color:#2F92EE;'>#化疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33580, encryptionId=7b8d3358050, topicName=化疗药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5f629793993, createdName=luwei03, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537770, encodeId=5420153e77012, content=<a href='/topic/show?id=1f9983082fa' target=_blank style='color:#2F92EE;'>#肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83082, encryptionId=1f9983082fa, topicName=肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ed1012894470, createdName=30397608, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581784, encodeId=aa0d1581e84a2, content=<a href='/topic/show?id=0813335e996' target=_blank style='color:#2F92EE;'>#化疗药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33579, encryptionId=0813335e996, topicName=化疗药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=298f16872689, createdName=12498cb5m18暂无昵称, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593741, encodeId=cc201593e4142, content=<a href='/topic/show?id=ff895565586' target=_blank style='color:#2F92EE;'>#抗肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55655, encryptionId=ff895565586, topicName=抗肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5e18156549, createdName=zhu_jun9843, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1239156, encodeId=d49b12391563d, content=👏👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33578272224, createdName=ms5000000900062349, createdTime=Tue Aug 16 23:28:25 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446822, encodeId=81f91446822d0, content=<a href='/topic/show?id=94bd830865e' target=_blank style='color:#2F92EE;'>#肿瘤药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83086, encryptionId=94bd830865e, topicName=肿瘤药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKneTxOtx0KRAPibib3sfmib4P2269UG6op6ZN5ZKddPvUibR7RfFob8X6FicRugoeY8Dicy4cibArjj168Q/132, createdBy=c17d5287383, createdName=smartjoy, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506731, encodeId=2ee61506e31cf, content=<a href='/topic/show?id=7b8d3358050' target=_blank style='color:#2F92EE;'>#化疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33580, encryptionId=7b8d3358050, topicName=化疗药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5f629793993, createdName=luwei03, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537770, encodeId=5420153e77012, content=<a href='/topic/show?id=1f9983082fa' target=_blank style='color:#2F92EE;'>#肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83082, encryptionId=1f9983082fa, topicName=肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ed1012894470, createdName=30397608, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581784, encodeId=aa0d1581e84a2, content=<a href='/topic/show?id=0813335e996' target=_blank style='color:#2F92EE;'>#化疗药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33579, encryptionId=0813335e996, topicName=化疗药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=298f16872689, createdName=12498cb5m18暂无昵称, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593741, encodeId=cc201593e4142, content=<a href='/topic/show?id=ff895565586' target=_blank style='color:#2F92EE;'>#抗肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55655, encryptionId=ff895565586, topicName=抗肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5e18156549, createdName=zhu_jun9843, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1239156, encodeId=d49b12391563d, content=👏👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33578272224, createdName=ms5000000900062349, createdTime=Tue Aug 16 23:28:25 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446822, encodeId=81f91446822d0, content=<a href='/topic/show?id=94bd830865e' target=_blank style='color:#2F92EE;'>#肿瘤药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83086, encryptionId=94bd830865e, topicName=肿瘤药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKneTxOtx0KRAPibib3sfmib4P2269UG6op6ZN5ZKddPvUibR7RfFob8X6FicRugoeY8Dicy4cibArjj168Q/132, createdBy=c17d5287383, createdName=smartjoy, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506731, encodeId=2ee61506e31cf, content=<a href='/topic/show?id=7b8d3358050' target=_blank style='color:#2F92EE;'>#化疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33580, encryptionId=7b8d3358050, topicName=化疗药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5f629793993, createdName=luwei03, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537770, encodeId=5420153e77012, content=<a href='/topic/show?id=1f9983082fa' target=_blank style='color:#2F92EE;'>#肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83082, encryptionId=1f9983082fa, topicName=肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ed1012894470, createdName=30397608, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581784, encodeId=aa0d1581e84a2, content=<a href='/topic/show?id=0813335e996' target=_blank style='color:#2F92EE;'>#化疗药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33579, encryptionId=0813335e996, topicName=化疗药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=298f16872689, createdName=12498cb5m18暂无昵称, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593741, encodeId=cc201593e4142, content=<a href='/topic/show?id=ff895565586' target=_blank style='color:#2F92EE;'>#抗肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55655, encryptionId=ff895565586, topicName=抗肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5e18156549, createdName=zhu_jun9843, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1239156, encodeId=d49b12391563d, content=👏👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33578272224, createdName=ms5000000900062349, createdTime=Tue Aug 16 23:28:25 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446822, encodeId=81f91446822d0, content=<a href='/topic/show?id=94bd830865e' target=_blank style='color:#2F92EE;'>#肿瘤药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83086, encryptionId=94bd830865e, topicName=肿瘤药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKneTxOtx0KRAPibib3sfmib4P2269UG6op6ZN5ZKddPvUibR7RfFob8X6FicRugoeY8Dicy4cibArjj168Q/132, createdBy=c17d5287383, createdName=smartjoy, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506731, encodeId=2ee61506e31cf, content=<a href='/topic/show?id=7b8d3358050' target=_blank style='color:#2F92EE;'>#化疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33580, encryptionId=7b8d3358050, topicName=化疗药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5f629793993, createdName=luwei03, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537770, encodeId=5420153e77012, content=<a href='/topic/show?id=1f9983082fa' target=_blank style='color:#2F92EE;'>#肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83082, encryptionId=1f9983082fa, topicName=肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ed1012894470, createdName=30397608, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581784, encodeId=aa0d1581e84a2, content=<a href='/topic/show?id=0813335e996' target=_blank style='color:#2F92EE;'>#化疗药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33579, encryptionId=0813335e996, topicName=化疗药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=298f16872689, createdName=12498cb5m18暂无昵称, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593741, encodeId=cc201593e4142, content=<a href='/topic/show?id=ff895565586' target=_blank style='color:#2F92EE;'>#抗肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55655, encryptionId=ff895565586, topicName=抗肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5e18156549, createdName=zhu_jun9843, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1239156, encodeId=d49b12391563d, content=👏👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33578272224, createdName=ms5000000900062349, createdTime=Tue Aug 16 23:28:25 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446822, encodeId=81f91446822d0, content=<a href='/topic/show?id=94bd830865e' target=_blank style='color:#2F92EE;'>#肿瘤药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83086, encryptionId=94bd830865e, topicName=肿瘤药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKneTxOtx0KRAPibib3sfmib4P2269UG6op6ZN5ZKddPvUibR7RfFob8X6FicRugoeY8Dicy4cibArjj168Q/132, createdBy=c17d5287383, createdName=smartjoy, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506731, encodeId=2ee61506e31cf, content=<a href='/topic/show?id=7b8d3358050' target=_blank style='color:#2F92EE;'>#化疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33580, encryptionId=7b8d3358050, topicName=化疗药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5f629793993, createdName=luwei03, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537770, encodeId=5420153e77012, content=<a href='/topic/show?id=1f9983082fa' target=_blank style='color:#2F92EE;'>#肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83082, encryptionId=1f9983082fa, topicName=肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ed1012894470, createdName=30397608, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581784, encodeId=aa0d1581e84a2, content=<a href='/topic/show?id=0813335e996' target=_blank style='color:#2F92EE;'>#化疗药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33579, encryptionId=0813335e996, topicName=化疗药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=298f16872689, createdName=12498cb5m18暂无昵称, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593741, encodeId=cc201593e4142, content=<a href='/topic/show?id=ff895565586' target=_blank style='color:#2F92EE;'>#抗肿瘤药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55655, encryptionId=ff895565586, topicName=抗肿瘤药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5e18156549, createdName=zhu_jun9843, createdTime=Thu Jul 14 09:20:44 CST 2022, time=2022-07-14, status=1, ipAttribution=)]

相关资讯

J Endod:颈环外吸收的容积评估方法以及它与分类、治疗方案和期望预后之间的联系

这篇研究的目的是提供一种对ECR病例的容积评估方法,并通过3名有资质的、独立的评估者确定其与Heithersay分类、治疗方案和预后的关系。

Eur Heart J:抗癌治疗引起的心脏毒性分类、患病率和结局

由此可见,大多数患者在癌症治疗期间或之后出现了心肌损伤/功能障碍的客观数据。但是,严重的CTox具有很强的预后关系,发生相对较少。

IEEE trans:利用空间信息增强基于EEG的抑郁症患者分类

抑郁症是最常见的抑郁障碍,以显著而持久的心境低落为主要临床特征,是心境障碍的主要类型。根据世卫组织统计,到2030年,抑郁症会成为全球的主要疾病之一。郁症发现得越早,越容易治疗。脑电图作为一种低成本、

Nat BME:通过自体荧光成像对T细胞活化分类

T细胞是适应性免疫反应的重要组成部分,在活化后具有多种细胞毒性,免疫调节作用。

心理医学科普:社交恐惧的分类及其识别

在青少年心理咨询与心理治疗的来访者中,社交恐惧占有相当的比例。运用逻辑学方法对社交恐惧进行分类,有助于寻找社交恐惧的主要原因,从而进一步找到缓解与消除社交恐惧的方法。 在心理咨询的实践中主要采用以下逻辑学方法进行分类。 1.人际熟识度划分:可分为对生人恐惧和对熟人恐惧。对生人恐惧的多与自卑心理有关,人际交往中自信不足、勇气不够、缺乏胆量。而对熟人恐惧的则多与挫折有关,特别是对某些特定熟

2019 SCAI心源性休克分类临床专家共识声明解读

2019 年5 月, 美国心血管造影和介入学会(SCAI)发布了《心原性休克分类临床专家共识声明》(以下简称《共识》),该共识提出了新的心原性休克标准分类方法,按照心原性休克的不同阶段分为A~E 五期[1]。该《共识》引起广泛关注。

Baidu
map
Baidu
map
Baidu
map