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Heart：阵发性房颤HCM患者易出现运动障碍

2013-12-16 高晓方 译 医学论坛网

阵发性房颤HCM肥厚型心肌病运动障碍
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美国一项研究表明，在肥厚型心肌病（HCM）患者中，阵发性房颤与运动障碍具有相关性。论文12月10日在线发表于《心脏》（Heart）。 房颤是HCM最常见的心律失常。此项研究共纳入265例HCM患者，并对其实施了心肺试验和呼出气分析。采集基线人口统计数据、病史和静息超声心动图。通过病历和基线心电图确认房颤诊断。阵发性房颤患者在接受心肺试验时为窦性心律。以峰值VO2<20 mL/kg/mi

美国一项研究表明，在肥厚型心肌病（HCM）患者中，阵发性房颤与运动障碍具有相关性。论文12月10日在线发表于《心脏》（Heart）。

房颤是HCM最常见的心律失常。此项研究共纳入265例HCM患者，并对其实施了心肺试验和呼出气分析。采集基线人口统计数据、病史和静息超声心动图。通过病历和基线心电图确认房颤诊断。阵发性房颤患者在接受心肺试验时为窦性心律。以峰值VO2<20 mL/kg/min定义运动障碍。利用多变量Logistic回归评估运动障碍与阵发性房颤的相关性。

结果显示，55例患者伴有房颤，其中阵发性和永久性房颤分别为28和27例。与无房颤者相比，阵发性房颤患者年龄较大，更有可能性应用抗心律失常和抗凝药物，并且左心房更大。阵发性房颤患者的峰值VO2较低（P=0.02），并且更有可能出现运动障碍（<0.001）。对年龄、性别和体质指数（BMI）进行校正之后，运动障碍仍与阵发性房颤显著相关（OR 4.65；P=0.001）。

原文出处：

Azarbal F, Singh M, Finocchiaro G, Le VV, Schnittger I, Wang P, Myers J, Ashley E, Perez M.Exercise capacity and paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy.Heart. 2013 Dec 10. doi: 10.1136/heartjnl-2013-304908. 

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    2013-12-18 zhaojie88

    #ART#

    0

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    2013-12-18 FukaiBao

    #运动障碍#

    0

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    2013-12-18 lqrandywkz

    #阵发性房颤#

    0

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    2013-12-18 仁者大医

    #HCM#

    0

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    2013-12-18 slcumt

    #HEART#

    0

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