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房间隔缺损封堵器治疗结核性支气管胸膜瘘一例

2013-07-19 萧弈 丁香园

     患者,男性,反复咳嗽,咳痰17年,确诊为双肺多药耐药肺结核。抗结核治疗2年,期间反复发作5次,计算机断层扫描未见改善。患者最终由于左肺感染性毁损接受了左全肺切除术,术后予以抗结核治疗。术后一月,患者出现高热,咳嗽。可曲式纤维支气管镜检查发现在左主支气管残端有一个5毫米小孔的支气管胸膜瘘(BPF)。痰和胸腔积液反复检查发现多药耐药性结核病合并白色念珠菌,铜绿假单胞菌和表皮葡萄球菌

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  患者,男性,反复咳嗽,咳痰17年,确诊为双肺多药耐药肺结核。抗结核治疗2年,期间反复发作5次,计算机断层扫描未见改善。患者最终由于左肺感染性毁损接受了左全肺切除术,术后予以抗结核治疗。术后一月,患者出现高热,咳嗽。可曲式纤维支气管镜检查发现在左主支气管残端有一个5毫米小孔的支气管胸膜瘘(BPF)。痰和胸腔积液反复检查发现多药耐药性结核病合并白色念珠菌,铜绿假单胞菌和表皮葡萄球菌感染。通过胸腔引流管引流,抗生素,抗真菌和超过17个月的抗结核药物治疗后感染症状稳定。然而,漏气持续无改善。由于瘘口的大小,MDR结核病,病人的状况不佳,决定不行胸廓成形术,而是尝试一种使用ASD封堵器的新型微创介入治疗。

  在双腔支气管插管全麻下,采用数字减影血管造影(DSA)用左支气管套管,通过导丝将ASD封堵器插入瘘口。封堵器被送到前盘位于胸膜腔和近盘位于左主支气管。通过气管导管DSA支气管镜检查证实的近盘的位置。

  患者成功进行了封堵手术,耐受性良好,没有任何手术相关并发症。胸腔引流管漏气立即停止。病人在术后不久呼吸困难改善,术后第3天胸腔引流管拔除。术后1个月,3个月,10个月,支气管镜检查发现瘘口完全封闭,肉芽组织已经渗透到左主支气管管腔周围封堵器的近端。6个月后计算机断层扫描发现封堵器完全堵塞瘘口。随访10个月,病人停止抗结核治疗,没有BPF症状。    

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    2013-09-03 lifestar
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