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Lancet:“颈痛2月”案例报道——罕见寄生虫感染

2015-11-06 Mechront 译 MedSci原创

一名5岁21-三体女孩,颈痛2月,检查未发现神经系统异常和皮肤异常。MRI示C2-C4区域基于硬脑膜的肿块,导致脊髓受压。难道是周围神经鞘瘤或脑膜瘤?不过这类肿瘤在儿童是罕见的。后行了硬膜内肿块切除术。组织病理学示:该肿块内包含一个,含丰富微丝蚴的怀孕的双子宫成年雌性线虫。显微镜下发现:角质层表面脊增厚,与盘尾属表现一致。术后18天行腰椎穿刺脑脊液中没有发现微丝蚴,眼部检查也没有发现明显异常。因担

一名5岁21-三体女孩,颈痛2月,检查未发现神经系统异常和皮肤异常。MRI示C2-C4区域基于硬脑膜的肿块,导致脊髓受压。难道是周围神经鞘瘤或脑膜瘤?不过这类肿瘤在儿童是罕见的。后行了硬膜内肿块切除术。

组织病理学示:该肿块内包含一个,含丰富微丝蚴的怀孕的双子宫成年雌性线虫。显微镜下发现:角质层表面脊增厚,与盘尾属表现一致。


术后18天行腰椎穿刺脑脊液中没有发现微丝蚴,眼部检查也没有发现明显异常。

因担心体内还有微丝蚴,开始使用伊维菌素和强力霉素进行治疗。

9个月后患者临床表现和影像学检查均提示没有复发。

目前并不知道患者为什么会感染上该寄生虫。她住在新墨西哥州西北农村,经常去她家附近的纳瓦霍人湖。对她家的两只狗进行眼睛和皮肤检查,没有发现盘尾属感染的证据。她没有离开过美国,也没有被动物或昆虫咬伤史。

截至目前,全世界共报道了21例人畜共患盘尾属感染,关于盘尾属寄生虫(Onchocerca lupi)感染的仅仅只有5例。与本篇类似的报道有1篇,一名同地理区域的年轻女孩,表现为颈痛和上颈椎包块。

原始出处:

Dudley RW, Smith C,et al.A cervical spine mass caused by Onchocerca lupi.Lancet. 2015 Oct 3;386(10001):1372.

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    2016-01-01 howi
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    2015-11-08 lovejing

    Onchocerca lupi 盘尾属 真的涨姿势了

    0

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    2015-11-08 changfy
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1828290, encodeId=106f1828290e3, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Jan 01 17:55:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42833, encodeId=b778428331b, content=Onchocerca lupi 盘尾属 真的涨姿势了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9e0b1603164, createdName=lovejing, createdTime=Sun Nov 08 13:49:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448876, encodeId=92ad14488e61c, content=<a href='/topic/show?id=32c61006366d' target=_blank style='color:#2F92EE;'>#颈痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100636, encryptionId=32c61006366d, topicName=颈痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52cb5448957, createdName=changfy, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467104, encodeId=42ed146e10411, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42720, encodeId=589142e2042, content=晕, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Sat Nov 07 08:17:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42715, encodeId=5f7842e15d2, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ee51614674, createdName=240612799, createdTime=Sat Nov 07 06:16:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42708, encodeId=153d42e0860, content=长见识了。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sat Nov 07 00:57:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42664, encodeId=981942664b9, content=涨姿势, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05151605011, createdName=linglong1990, createdTime=Fri Nov 06 14:56:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
    2015-11-07 午夜星河

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1828290, encodeId=106f1828290e3, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Jan 01 17:55:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42833, encodeId=b778428331b, content=Onchocerca lupi 盘尾属 真的涨姿势了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9e0b1603164, createdName=lovejing, createdTime=Sun Nov 08 13:49:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448876, encodeId=92ad14488e61c, content=<a href='/topic/show?id=32c61006366d' target=_blank style='color:#2F92EE;'>#颈痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100636, encryptionId=32c61006366d, topicName=颈痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52cb5448957, createdName=changfy, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467104, encodeId=42ed146e10411, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42720, encodeId=589142e2042, content=晕, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Sat Nov 07 08:17:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42715, encodeId=5f7842e15d2, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ee51614674, createdName=240612799, createdTime=Sat Nov 07 06:16:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42708, encodeId=153d42e0860, content=长见识了。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sat Nov 07 00:57:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42664, encodeId=981942664b9, content=涨姿势, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05151605011, createdName=linglong1990, createdTime=Fri Nov 06 14:56:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
    2015-11-07 240612799

    罕见

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1828290, encodeId=106f1828290e3, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Jan 01 17:55:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42833, encodeId=b778428331b, content=Onchocerca lupi 盘尾属 真的涨姿势了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9e0b1603164, createdName=lovejing, createdTime=Sun Nov 08 13:49:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448876, encodeId=92ad14488e61c, content=<a href='/topic/show?id=32c61006366d' target=_blank style='color:#2F92EE;'>#颈痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100636, encryptionId=32c61006366d, topicName=颈痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52cb5448957, createdName=changfy, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467104, encodeId=42ed146e10411, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42720, encodeId=589142e2042, content=晕, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Sat Nov 07 08:17:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42715, encodeId=5f7842e15d2, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ee51614674, createdName=240612799, createdTime=Sat Nov 07 06:16:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42708, encodeId=153d42e0860, content=长见识了。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sat Nov 07 00:57:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42664, encodeId=981942664b9, content=涨姿势, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05151605011, createdName=linglong1990, createdTime=Fri Nov 06 14:56:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
    2015-11-07 lecoo

    长见识了。。。

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1828290, encodeId=106f1828290e3, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Jan 01 17:55:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42833, encodeId=b778428331b, content=Onchocerca lupi 盘尾属 真的涨姿势了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9e0b1603164, createdName=lovejing, createdTime=Sun Nov 08 13:49:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448876, encodeId=92ad14488e61c, content=<a href='/topic/show?id=32c61006366d' target=_blank style='color:#2F92EE;'>#颈痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100636, encryptionId=32c61006366d, topicName=颈痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52cb5448957, createdName=changfy, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467104, encodeId=42ed146e10411, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sun Nov 08 01:55:00 CST 2015, time=2015-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42720, encodeId=589142e2042, content=晕, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Sat Nov 07 08:17:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42715, encodeId=5f7842e15d2, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ee51614674, createdName=240612799, createdTime=Sat Nov 07 06:16:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42708, encodeId=153d42e0860, content=长见识了。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sat Nov 07 00:57:00 CST 2015, time=2015-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42664, encodeId=981942664b9, content=涨姿势, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05151605011, createdName=linglong1990, createdTime=Fri Nov 06 14:56:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
    2015-11-06 linglong1990

    涨姿势

    0

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