美国MIT教授Robert Weinberg撤销一篇Cancer research论文

2015-07-07 佚名 MedSci原创整理

据Retraction Watch网站消息，由于数据出现问题，美国麻省理工学院Robert Weinberg教授撤销一篇Cancer research论文。该论文主要研究癌症转移过程中的分子机制。《癌症研究》发出通告称，作者发现论文中部分数据是由不同批次实验拼凑而成，随后要求撤稿，并对此引起的不便表示歉意。该论文的第一作者Scott Valastyan曾获得2011年的哈佛Runy

据Retraction Watch网站消息，由于数据出现问题，美国麻省理工学院Robert Weinberg教授撤销一篇Cancer research论文。

该论文主要研究癌症转移过程中的分子机制。《癌症研究》发出通告称，作者发现论文中部分数据是由不同批次实验拼凑而成，随后要求撤稿，并对此引起的不便表示歉意。

该论文的第一作者Scott Valastyan曾获得2011年的哈佛Runyon基金，该基金主要资助优秀的博士后从事癌症方面的研究，为期三年，共156000美元。但Scott Valastyan自2012年后就没有再发表过文章。
据悉，这是Robert Weinberg因数据问题撤销的第五篇论文。此前还撤消一篇Cell文章：美国麻省理工学院教授撤销一篇《细胞》论文

通过Thomson 的WOS检索得知，这篇文章“Concurrent Suppression of Integrin α5, Radixin, and RhoA Phenocopies the Effects of miR-31 on Metastasis,”已被全球研究者引用高达70次。Robert Weinberg一直被认为是肿瘤领域研究的先锋人物。

关于Robert A.Weinberg教授：

Robert A.Weinberg身上笼罩着一道道绚丽的光环：美国科学院院士，世界着名的Whitehead研究所创始人之一，他曾发现了第一个人类癌基因Ras和第一个抑癌基因Rb，他的一系列杰出研究工作已经成为肿瘤研究领域乃至整个医学生物学领域的重要里程碑。

几十年来，Weinberg教授在《自然》、《科学》、《细胞》等国际顶尖科学杂志上发表了一系列高水平的科研论文，著有《癌生物学》一书。荣获过美国国家科学奖章、Bristol-Myers Award、美国癌症研究学会兰登基金会奖、Wolf医学奖、Otto Warburg奖章等多项重大科技奖项，并被《Discover》评选为年度科学家。他的一系列杰出研究工作已经成为肿瘤研究领域乃至整个医学生物学领域的重要里程碑。

这位科学家发表的研究论文一向倍受关注——今年3月Weinberg教授在Cell杂志上，发表了一篇综述：Hallmarks of Cancer: The Next Generation，这篇综述是前一综述：The Hallmarks of Cancer的升级版。“The Hallmarks of Cancer”这篇文章介绍了肿瘤细胞的六大基本特征，被称为肿瘤学研究的经典论文，到目前为止，这篇论文已经被引用了上万次。

最新综述同样也是与Douglas Hanahan合作，论文长达29页，简述了最近10年肿瘤学中的热点和进展，包括细胞自噬、肿瘤干细胞、肿瘤微环境等等，并且将原有的肿瘤细胞六大特征扩增到了十个，这十个特征分别是：自给自足生长信号（Self-Sufficiency in Growth Signals）；抗生长信号的不敏感（Insensitivity to Antigrowth Signals）；抵抗细胞死亡(Resisting Cell Death)；潜力无限的复制能力(Limitless Replicative Potential)；持续的血管生成(Sustained Angiogenesis)；组织浸润和转移(Tissue Invasion and Metastasis)；避免免疫摧毁(Avoiding Immune Destruction)；促进肿瘤的炎症（Tumor Promotion Inflammation）；细胞能量异常（Deregulating Cellular Energetics）；基因组不稳定和突变（Genome Instability and Mutation）。

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2015-12-15 gracezdd

#MIT#

70 0
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2016-06-09 12498e5fm12(暂无昵称)

#Ｒobert#

64 0
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2015-07-09 jiafufeng@yaho

#撤销#

58 0
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2015-07-09 yangshch

#Research#

52 0
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2015-07-08 huaxipanxing

看看

137 0
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2015-07-08 Jianghuiqin

可以去关注一下~

108 0
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2015-07-08 保守主义

没说清原因啊

81 0
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2015-07-08 保守主义

不过听上去还是很厉害

172 0
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2015-07-07 Gsurgeon

学习了不错

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