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Clin Gastroenterol Hepatol:超加工食品可增加克罗恩病的发生风险

2021-09-02 Nebula MedSci原创

超加工食品摄入量与克罗恩病风险呈正相关!

在过去几十年里,西化地区炎症性肠病发病率的上升与超加工食品 (UPF) 消费量的增长相吻合。本研究旨在评估 UPF 的消耗与克罗恩病 (CD) 和溃疡性结肠炎 (UC) 两种炎症性肠病风险之间的相关性。

超加工食品是在已经加工过的食品基础上再加工的食品,这类食品通常含有五种以上工业制剂,并且是高糖、高脂、高热量的食品,长期食用会增加患癌风险。

这是一项全国性的关于医务工作者的前瞻性研究,纳入了三个队列的受试者:护士健康研究(1986-2014)、护士健康研究 2(1991-2017)和卫生专业人员随访研究(1986-2012)。采用了Cox比例风险模型根据自我报告的 UPF 消耗量评估 CD 和 UC 的风险比。

共纳入了245,112位受试者。在随访了5,468,444 人·年期间,共记录了 369 例 CD 和488 例 UC。炎症性肠病的中位确诊年龄为 56 岁(范围 29-85)。

超加工食品摄入量与克罗恩病和溃疡性结肠炎风险的相关性

与 UPF 消耗最低的四分位受试者相比,UPF 消耗最高四分位的受试者罹患 CD 的风险显著增加(HR 1.70; 95%CI 1.23-2.35;p=0.0008)。在不同的 UPF 亚组中,超加工的面包和早餐食品;冷冻或常温的即食/热食;酱汁、奶酪、涂抹酱和肉汁与 CD 风险正相关性最强(摄入量每增加一个标准差的风险比[HR]分别是 1.18 [95%CI 1.07-1.29]; 1.11 [1.01-1.22] 和 1.14 [1.02-1.27])。

UPF 摄入量与 UC 风险之间没有明显关联。

综上所述,较高的超加工食品摄入量与发生克罗恩病的风险增加有关。不同种类的超加工食品对克罗恩病风险的贡献度不同,需进一步细化研究。

原始出处:

Lo Chun-Han,Khandpur Neha,Rossato Sinara Laurini et al. Ultra-processed foods and risk of Crohn's disease and ulcerative colitis: a prospective cohort study.[J] .Clin Gastroenterol Hepatol, 2021, https://doi.org/10.1016/j.cgh.2021.08.031

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    2022-06-25 许安
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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-04 gwc384
  5. [GetPortalCommentsPageByObjectIdResponse(id=2065430, encodeId=f6712065430ba, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Feb 27 15:41:51 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712910, encodeId=69411e1291089, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Feb 03 06:41:51 CST 2022, time=2022-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2073428, encodeId=b7ff20e34286d, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Jun 25 16:41:51 CST 2022, time=2022-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1427550, encodeId=b85a142e550b0, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Sep 04 02:41:51 CST 2021, time=2021-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013841, encodeId=507410138413f, content=可以用于指导临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/449c3f6b60e44525935c6d20f692180c/575c41cb44494ec18c17a52ba43d9d82.jpg, createdBy=e4725480342, createdName=我是杜樟锋, createdTime=Thu Sep 02 19:00:43 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013814, encodeId=a1d71013814ae, content=值得进一步研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-02 我是杜樟锋

    可以用于指导临床

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2065430, encodeId=f6712065430ba, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Feb 27 15:41:51 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712910, encodeId=69411e1291089, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Feb 03 06:41:51 CST 2022, time=2022-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2073428, encodeId=b7ff20e34286d, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Jun 25 16:41:51 CST 2022, time=2022-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1427550, encodeId=b85a142e550b0, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Sep 04 02:41:51 CST 2021, time=2021-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013841, encodeId=507410138413f, content=可以用于指导临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/449c3f6b60e44525935c6d20f692180c/575c41cb44494ec18c17a52ba43d9d82.jpg, createdBy=e4725480342, createdName=我是杜樟锋, createdTime=Thu Sep 02 19:00:43 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013814, encodeId=a1d71013814ae, content=值得进一步研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-02 ms6000001832119769

    值得进一步研究

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2065430, encodeId=f6712065430ba, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Feb 27 15:41:51 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712910, encodeId=69411e1291089, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Feb 03 06:41:51 CST 2022, time=2022-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2073428, encodeId=b7ff20e34286d, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Jun 25 16:41:51 CST 2022, time=2022-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1427550, encodeId=b85a142e550b0, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Sep 04 02:41:51 CST 2021, time=2021-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013841, encodeId=507410138413f, content=可以用于指导临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/449c3f6b60e44525935c6d20f692180c/575c41cb44494ec18c17a52ba43d9d82.jpg, createdBy=e4725480342, createdName=我是杜樟锋, createdTime=Thu Sep 02 19:00:43 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013814, encodeId=a1d71013814ae, content=值得进一步研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-02 ms2000001730191797

    有用的话题

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2065430, encodeId=f6712065430ba, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Feb 27 15:41:51 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712910, encodeId=69411e1291089, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Sep 04 02:41:51 CST 2021, time=2021-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013841, encodeId=507410138413f, content=可以用于指导临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/449c3f6b60e44525935c6d20f692180c/575c41cb44494ec18c17a52ba43d9d82.jpg, createdBy=e4725480342, createdName=我是杜樟锋, createdTime=Thu Sep 02 19:00:43 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013814, encodeId=a1d71013814ae, content=值得进一步研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-02 ms5000000518166734

    已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2065430, encodeId=f6712065430ba, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Feb 27 15:41:51 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712910, encodeId=69411e1291089, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Feb 03 06:41:51 CST 2022, time=2022-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2073428, encodeId=b7ff20e34286d, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Jun 25 16:41:51 CST 2022, time=2022-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1427550, encodeId=b85a142e550b0, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Sep 04 02:41:51 CST 2021, time=2021-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013841, encodeId=507410138413f, content=可以用于指导临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/449c3f6b60e44525935c6d20f692180c/575c41cb44494ec18c17a52ba43d9d82.jpg, createdBy=e4725480342, createdName=我是杜樟锋, createdTime=Thu Sep 02 19:00:43 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013814, encodeId=a1d71013814ae, content=值得进一步研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-02 ms8000001940906233

    简简单单才是真

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=2065430, encodeId=f6712065430ba, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Feb 27 15:41:51 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712910, encodeId=69411e1291089, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4dcb5439452, createdName=ms6000001832119769, createdTime=Thu Sep 02 17:12:33 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013786, encodeId=f1e41013e8613, content=有用的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5425563316, createdName=ms2000001730191797, createdTime=Thu Sep 02 15:52:01 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013753, encodeId=dcf11013e53a7, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Thu Sep 02 13:23:06 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013745, encodeId=0c8f1013e453a, content=简简单单才是真, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b2915592493, createdName=ms8000001940906233, createdTime=Thu Sep 02 12:29:58 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1013734, encodeId=82901013e3472, content=多吃粗粮, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210426/73219cf589ee4ccf8e1ba02a58015712/c838adb9e8ab45b3b3bfeead3cc8cf36.jpg, createdBy=32761995973, createdName=DRMORTON, createdTime=Thu Sep 02 11:49:56 CST 2021, time=2021-09-02, status=1, ipAttribution=)]
    2021-09-02 DRMORTON

    多吃粗粮

    0

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