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NEJM:航天中心医院医生在新英格兰医学杂志发表了一个心电图,你能否看出端倪?

2018-04-27 文韬 中国循环杂志

这是一名36岁的男性,以持续性胸骨后紧缩感6小时来到急诊。最初胸部不适呈间断性,但1小时前转为持续性。该患者吸烟,为10包/年。

近期,航天中心医院赵运涛在新英格兰医学杂志发表了一个心电图的个案。

这是一名36岁的男性,以持续性胸骨后紧缩感6小时来到急诊。最初胸部不适呈间断性,但1小时前转为持续性。该患者吸烟,为10包/年。

心电图如图所示, V2至V5导联ST段压低,T波高耸对称。



检测肌钙蛋白I正常。

胸前导联的这种ST段呈上斜型下移,随后T波对称高尖有时称为de Winter图形,这与近端左前降支冠状动脉闭塞有关。

患者立即行冠状动脉造影,手术显示近端冠状动脉左前降支95%狭窄(B,箭头),之后植入一枚支架(C)。



手术后14小时,肌钙蛋白I水平上升至7.19 ng/ml(正常值<0.06)的峰值。后续过程心电图显示ST段和T波改变的演变,在导联I、aVL和V2-V6出现T波倒置。



2008年荷兰鹿特丹心内科医生de Winter等人通过回顾其心脏中心1532例左前降支(LAD)近段闭塞的急性冠脉综合征心电图发现,其中有30例并未出现典型ST段抬高的心肌梗死(STEMI)超急性期ECG表现模式。作者将这一发现,以Letter的形式发表在《新英格兰医学杂志》。



虽然de Winter发表的既非个案报道、也非论着,但大牌杂志的号召力使得这一心电现象迅速为人所知,相关文献报道逐年增多,并理所当然的被业界称为de winter综合征、de winter-T波改变,成为近年来为数不多的以人名命名的疾病。

或许,这种心电图改变在许多心电图和心内科医生眼中都似曾相似,但只有那些善于总结发表的作者才能占得头功。

对“非常规”现象的视而不见和缺乏深入挖掘的精神,是医学界迄今都缺乏国人首先发现某类疾病的根源所在。

原始出处:Zhao YT, Huang YS. ECG Pattern Associated with Left Anterior Descending Coronary Artery Occlusion. N Engl J Med. 2018 Apr 19;378(16):e22.

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    2018-08-21 蓝米

    重视非常规现象,善于积累挖掘

    0

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    2018-04-28 张新亮1853311252142e2fm

    好文献学习啦

    0

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    2018-04-28 1dd8c52fm63(暂无匿称)

    了解了解.继续关注

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1748674, encodeId=dcaf1e486744b, content=<a href='/topic/show?id=52d15861349' target=_blank style='color:#2F92EE;'>#新英格兰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58613, encryptionId=52d15861349, topicName=新英格兰)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=db3e36178621, createdName=shalley78, createdTime=Sun Aug 19 03:42:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339965, encodeId=add033996597, content=重视非常规现象,善于积累挖掘, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/b92a284ca410444bb616671ef4ba7db7/7230cc54d45245f59b538d2d4776c930.jpg, createdBy=8dc12379619, createdName=蓝米, createdTime=Tue Aug 21 18:20:06 CST 2018, time=2018-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480116, encodeId=b6781480116b2, content=<a href='/topic/show?id=311b58614a5' target=_blank style='color:#2F92EE;'>#新英格兰医学杂志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58614, encryptionId=311b58614a5, topicName=新英格兰医学杂志)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fec7610558, createdName=ms9476844295372110, createdTime=Sun Apr 29 14:42:00 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309978, encodeId=bb983099e851, content=好文献学习啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat Apr 28 06:44:09 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309954, encodeId=589030995444, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sat Apr 28 05:57:56 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309930, encodeId=01db30993098, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sat Apr 28 05:18:35 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309908, encodeId=9fe630990878, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Apr 28 00:06:48 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309901, encodeId=73b930990158, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:12 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-28 121832a9m88暂无昵称

    学习了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1748674, encodeId=dcaf1e486744b, content=<a href='/topic/show?id=52d15861349' target=_blank style='color:#2F92EE;'>#新英格兰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58613, encryptionId=52d15861349, topicName=新英格兰)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=db3e36178621, createdName=shalley78, createdTime=Sun Aug 19 03:42:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339965, encodeId=add033996597, content=重视非常规现象,善于积累挖掘, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/b92a284ca410444bb616671ef4ba7db7/7230cc54d45245f59b538d2d4776c930.jpg, createdBy=8dc12379619, createdName=蓝米, createdTime=Tue Aug 21 18:20:06 CST 2018, time=2018-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480116, encodeId=b6781480116b2, content=<a href='/topic/show?id=311b58614a5' target=_blank style='color:#2F92EE;'>#新英格兰医学杂志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58614, encryptionId=311b58614a5, topicName=新英格兰医学杂志)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fec7610558, createdName=ms9476844295372110, createdTime=Sun Apr 29 14:42:00 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309978, encodeId=bb983099e851, content=好文献学习啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat Apr 28 06:44:09 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309954, encodeId=589030995444, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sat Apr 28 05:57:56 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309930, encodeId=01db30993098, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sat Apr 28 05:18:35 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309908, encodeId=9fe630990878, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Apr 28 00:06:48 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309901, encodeId=73b930990158, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:12 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-28 戒馋,懒,贪

    谢谢分享学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1748674, encodeId=dcaf1e486744b, content=<a href='/topic/show?id=52d15861349' target=_blank style='color:#2F92EE;'>#新英格兰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58613, encryptionId=52d15861349, topicName=新英格兰)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=db3e36178621, createdName=shalley78, createdTime=Sun Aug 19 03:42:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339965, encodeId=add033996597, content=重视非常规现象,善于积累挖掘, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/b92a284ca410444bb616671ef4ba7db7/7230cc54d45245f59b538d2d4776c930.jpg, createdBy=8dc12379619, createdName=蓝米, createdTime=Tue Aug 21 18:20:06 CST 2018, time=2018-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480116, encodeId=b6781480116b2, content=<a href='/topic/show?id=311b58614a5' target=_blank style='color:#2F92EE;'>#新英格兰医学杂志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58614, encryptionId=311b58614a5, topicName=新英格兰医学杂志)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fec7610558, createdName=ms9476844295372110, createdTime=Sun Apr 29 14:42:00 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309978, encodeId=bb983099e851, content=好文献学习啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat Apr 28 06:44:09 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309954, encodeId=589030995444, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sat Apr 28 05:57:56 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309930, encodeId=01db30993098, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sat Apr 28 05:18:35 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309908, encodeId=9fe630990878, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Apr 28 00:06:48 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309901, encodeId=73b930990158, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:12 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-27 wqkm

    ^_^^_^^_^

    0

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