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JACC:右心室功能不全常共存心源性恶病质

2013-08-07 高晓方 译 cmt

捷克一项研究表明,右心室功能不全和心源性恶病质往往共存;二者具有附加不良影响,并可能存在相关机制。论文7月在线发表于《美国心脏病学会杂志》(J Am Coll Cardiol)。 此项研究共纳入408例晚期心衰患者,并对身体成分(皮肤壁厚度)、超声心动图和血液检测进行了前瞻性评估。对受试者进行以死亡、移植或循环辅助装置应用为定义的不良事件随访。 结果显示,伴右心室

捷克一项研究表明,右心室功能不全和心源性恶病质往往共存;二者具有附加不良影响,并可能存在相关机制。论文7月在线发表于《美国心脏病学会杂志》(J Am Coll Cardiol)。

此项研究共纳入408例晚期心衰患者,并对身体成分(皮肤壁厚度)、超声心动图和血液检测进行了前瞻性评估。对受试者进行以死亡、移植或循环辅助装置应用为定义的不良事件随访。

结果显示,伴右心室功能不全的受试者(51%)体质指数(BMI)较低,体脂指数较低,并且更有可能出现恶病质(19%)。右心室功能不全程度与既往体重减轻较多以及脂体重/瘦体重比较低具有相关性。中位随访541天期间共发生150起不良事件(37%)。在伴右心室功能不全和恶病质的受试者中事件风险较高。BMI增加与事件发生率较低相关,并且该保护效应由脂肪量较高而非去脂体重指数介导。

Vojtech Melenovsky; Martin Kotrc; Barry A. Borlaug; Tomas Marek; Jan Kovar; Ivan Malek; Josef Kautzner.Relationships between Right Ventricular Function, Body Composition and Prognosis in Advanced Heart Failure.J Am Coll Cardiol. 2013;():. doi:10.1016/j.jacc.2013.06.046

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    2014-01-02 hbwxf
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    2013-09-13 wincls
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1853243, encodeId=99341853243e0, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jan 02 00:21:00 CST 2014, time=2014-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935824, encodeId=e59a193582447, content=<a href='/topic/show?id=39b5386288c' target=_blank style='color:#2F92EE;'>#右心室功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38628, encryptionId=39b5386288c, topicName=右心室功能)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3fb2500073, createdName=124987cdm26暂无昵称, createdTime=Wed Apr 02 08:21:00 CST 2014, time=2014-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693085, encodeId=3b251693085fa, content=<a href='/topic/show?id=f07d529e6ca' target=_blank style='color:#2F92EE;'>#恶病质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52976, encryptionId=f07d529e6ca, topicName=恶病质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3cd929335736, createdName=wincls, createdTime=Fri Sep 13 17:21:00 CST 2013, time=2013-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324838, encodeId=f4e513248383e, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Aug 09 06:21:00 CST 2013, time=2013-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543739, encodeId=e99c1543e39e3, content=<a href='/topic/show?id=52d93862e06' target=_blank style='color:#2F92EE;'>#右心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38627, encryptionId=52d93862e06, topicName=右心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18d13610637, createdName=124988c7m99暂无昵称, createdTime=Fri Aug 09 06:21:00 CST 2013, time=2013-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593402, encodeId=71d1159340203, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Fri Aug 09 06:21:00 CST 2013, time=2013-08-09, status=1, ipAttribution=)]
    2013-08-09 mhm295
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