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Clin Gastr Hepatol:适宜睡眠减少患溃疡性结肠炎的风险

2014-10-24 佚名 生物谷

近日,刊登在国际杂志Clinical Gastroenterology and Hepatology上的两篇研究论文中,来自麻省总医院的研究人员表示,如果个体每晚没有达到7-8小时的睡眠时间,那么其患溃疡性结肠炎的风险就会增加。 研究者Ashwin N. Ananthakrishnan说道,睡眠时间太短或太长都会对个体的健康带来影响,而且其和个体的总死亡率、心脑血管疾病及癌症的风险增加直接相关;

近日,刊登在国际杂志Clinical Gastroenterology and Hepatology上的两篇研究论文中,来自麻省总医院的研究人员表示,如果个体每晚没有达到7-8小时的睡眠时间,那么其患溃疡性结肠炎的风险就会增加。

研究者Ashwin N. Ananthakrishnan说道,睡眠时间太短或太长都会对个体的健康带来影响,而且其和个体的总死亡率、心脑血管疾病及癌症的风险增加直接相关;我们的研究发现,睡眠时间或许和溃疡性结肠炎的发生也息息相关。每天低于6小时或高于9小时的睡眠会增加个体患溃疡性结肠炎的风险。

文章中,研究者对1976年及1989年招募的女性个体进行了一项前瞻性研究,对其中90%以上的个体进行调查问卷;研究者指出,进行大量人群的长期研究可以更加清晰地揭示睡眠持续时间和潜在疾病发生风险之间的关联。而研究结果也显示,在睡眠持续时间和溃疡性结肠炎的发生风险之间存在一种U型关系,即睡眠时间过短或过长都会增加个体患溃疡性结肠炎的风险。

此前研究中,研究者报道了,较差的睡眠质量会使得个体患克罗恩病的风险增加两倍,而所有的数据也支持了人们对睡眠的破坏对免疫系统有影响这一论断,而睡眠的持续时间和睡眠质量也是衡量炎性肠病患者健康的重要参数。未来研究中研究人员希望通过进行更为深入的研究来解释睡眠影响机体肠炎的分子机制。

原始出处

Ananthakrishnan AN1, Khalili H2, Konijeti GG2, Higuchi LM3, de Silva P4, Fuchs CS5, Richter JM2, Schernhammer ES6, Chan AT7.Sleep Duration Affects Risk for Ulcerative Colitis: A Prospective Cohort Study.Clin Gastroenterol Hepatol. 2014 Apr 26

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    2015-06-10 许安
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    2015-08-06 nymo
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    2014-10-26 gwc384
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