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克罗恩病患者转归与专科护理的提高相关

2011-08-02 MedSci原创 MedSci原创

来源:医学论坛网   加拿大学者Geoffrey C. Nguyen等,最近在《胃肠病学》(Gastroenterology)杂志上发表了一篇报道,说明在加拿大曼尼托巴省,与1996年之前诊断克罗恩病(CD)的患者相比,1996后的诊断者的手术风险降低,这种降低还与专科护理相关;诊断1年内进行专科护理有可能改善CD患者的转归。   研究者们对在1988年至2008年间在加拿大曼尼托巴省诊断为C

来源:医学论坛网

  加拿大学者Geoffrey C. Nguyen等,最近在《胃肠病学》(Gastroenterology)杂志上发表了一篇报道,说明在加拿大曼尼托巴省,与1996年之前诊断克罗恩病(CD)的患者相比,1996后的诊断者的手术风险降低,这种降低还与专科护理相关;诊断1年内进行专科护理有可能改善CD患者的转归。

  研究者们对在1988年至2008年间在加拿大曼尼托巴省诊断为CD的3403例患者,进行了回顾性研究。被试者根据诊断年份被指定到不同的队列:队列I(1996年之前),队列II(1996~2000),或队列III(2001年及以后)。研究人员在这些队列间比较了手术和住院的风险,评估了免疫调节剂和专科护理的使用。

  队列I、II,和III的第一次手术的5年风险,分别为30%、22%,和18%。队列II和III与队列I相比,校正后的第一次手术危险比分别为0.72【95%可信区间(CI), 0.62~0.84】和0.57(95% CI,0.48~0.68)。队列III与队列II相比,校正后的危险比为0.79(95% CI,0.65~0.97)。在队列II和III诊断的第一年之内,有更高的消化科医师访问率(队列I,53%;队列II,72%;队列III,88%;P<0.0001),这与手术需要率的降低(危险比是危险比;95% CI为0.71~0.98)相关,并且促成了队列间的不同的手术率。诊断第一年内的免疫调节剂的使用,队列III高于队列II(20%比11%;P<0.0001)。

相关链接:Outcomes of Patients With Crohn's Disease Improved From 1988 to 2008 and Were Associated With Increased Specialist Care

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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    2015-01-11 zczcz6655

    学习了 好东西

    0

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