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JAMA:严重肺病又不想住院?福音来了!

2017-05-22 sunshine2015 来宝网

患有严重肺部疾病的患者可能会因为英国由位于伦敦的Guy's和St Thomas的Lane Fox呼吸服务团队领导的专家进行的“游戏变化”临床试验而转变生活。HOT-HMV试验(家用氧疗——家用机械通气),其中包括给予选定的患者在氧气治疗之外家中使用的呼吸机,被发现在急性感染后减少再入院率。

患有严重肺部疾病的患者可能会因为英国由位于伦敦的Guy's和St Thomas的Lane Fox呼吸服务团队领导的专家进行的“游戏变化”临床试验而转变生活。

HOT-HMV试验(家用氧疗——家用机械通气),其中包括给予选定的患者在氧气治疗之外家中使用的呼吸机,被发现在急性感染后减少再入院率。

已在美国医学协会杂志(JAMA)上发表的试验结果今天在华盛顿特区举行的美国胸科协会著名年会上公布。

仅在英国,每年约有3万人死于慢性阻塞性肺疾病(COPD)。世界卫生组织(WHO)估计,到2020年,COPD将是世界第三大杀手。

慢性阻塞性肺疾病(COPD)是用于描述进行性肺疾病(包括肺气肿,慢性支气管炎,难治性(不可逆))哮喘和某些形式的支气管扩张症的总称。这种疾病的特征是呼吸加促。

呼吸专家尼古拉斯·哈特教授和协调全国圣托马斯医院试验的帕特里克·墨菲博士表示,试验结果可为全球影响最严重的COPD患者的治疗方式铺平道路。

哈特教授解释道:“目前我们唯一需要给予这些患者的治疗方法是氧疗,但现在我们可以在家里给他们氧气和呼吸机,我们设法将再入院的可能性降低了近50% 。

“在试验中,我们使用家用呼吸机来协调患者的呼吸,面罩呼吸机通过吹入空气和氧气来保持氧气水平高,二氧化碳和废气低。

慢性阻塞性肺疾病是世界上最大的凶手之一,但是将家用呼吸机添加到氧气治疗中可以减少住院费用并维持生活质量。

来自布莱顿的74岁的Ronnie Ward已经患有COPD五年,每天晚上使用他的家用呼吸机来支持他的呼吸。自从被征召入试验以来,他和妻子Julie(55岁)不得不远离医院。

她说:“Ronnie进出医院,有时候会在病房里呆几个星期和几个月,来去花费很多时间,在医院里压力很大,非常沮丧。”

“我们发现,他出院后的几周内,Ronnie需要重新入院,因为他正在努力呼吸,每天晚上使用呼吸机给我们带来了很大压力。”

同时,随着病人的监测,未来三,五年的生存率将继续进行。

哈特教授说:“这些结果非常有希望,但工作将继续下去,到目前为止,我们发现使用家用呼吸机的家庭用氧气患者在28天内再次入院的可能性降低了三分之二。

“这是非常重要的,因为它不仅保持了患者的生活质量,而且还有可能显着提高我们照顾这些患者的能力,而不需要住院时间。在Guy和圣托马斯,约1000名患者每年接受COPD,如果我们能够让他们在家里舒服的时间更长,这将产生很大的影响。”

原始出处:

Patrick B. Murphy, Sunita Rehal, et al. Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation. JAMA. Published online May 21, 2017. doi:10.1001/jama.2017.4451

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    2017-07-22 amy0559
  2. [GetPortalCommentsPageByObjectIdResponse(id=1671853, encodeId=360916e18530b, content=<a href='/topic/show?id=58378220131' target=_blank style='color:#2F92EE;'>#肺病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82201, encryptionId=58378220131, topicName=肺病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2f0826868454, createdName=amy0559, createdTime=Sat Jul 22 07:58:00 CST 2017, time=2017-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203894, encodeId=dd77203894a3, content=学习了,值得期待, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Mon May 29 07:49:10 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201680, encodeId=33bd20168009, content=新的技术来临,好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue May 23 14:03:17 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201264, encodeId=0a9d20126494, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCkPCv9CVFBmWOibyBArQwSeQLxvxz9OaumlaSUZjfCWTxbXduhuG2xCJUPs1nB9nd4gxZknH7IZj/0, createdBy=52281985209, createdName=damiao93, createdTime=Mon May 22 14:21:44 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201259, encodeId=dbba2012599b, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon May 22 14:13:17 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201247, encodeId=e5b220124eb1, content=HOT-HMV试验(家用氧疗——家用机械通气),其中包括给予选定的患者在氧气治疗之外家中使用的呼吸机,被发现在急性感染后减少再入院率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 22 13:46:36 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201235, encodeId=dafc201235ed, content=学习了,不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhQkEvDREF6S2vZq3ZIpUYjdqicKVoAWaJSGoe8xNvS6o6QpmOlh2AQ7xuUpj8NiaDjJJgjbc7Xj3T6/0, createdBy=1c242047915, createdName=daiyaozu, createdTime=Mon May 22 13:02:17 CST 2017, time=2017-05-22, status=1, ipAttribution=)]
    2017-05-29 杨利洪

    学习了,值得期待

    0

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    2017-05-23 惠映实验室

    新的技术来临,好好学习

    0

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    2017-05-22 damiao93

    学习了,谢谢

    0

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    2017-05-22 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0

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    2017-05-22 有备才能无患

    HOT-HMV试验(家用氧疗——家用机械通气),其中包括给予选定的患者在氧气治疗之外家中使用的呼吸机,被发现在急性感染后减少再入院率。

    0

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    2017-05-22 daiyaozu

    学习了,不错

    0

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