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Diabetic Med:在糖耐量正常的中国人群中,血清1,5-脱水葡萄糖醇水平的降低与一级糖尿病家族史存在有关

2018-03-30 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于糖耐量正常的中国人群中,血清1,5-脱水葡萄糖醇水平的降低与一级糖尿病家族史存在有关的研究。本研究旨在探讨中国糖尿病一级亲属(FDR)HbA 1c,糖化白蛋白(GA)和1,5-脱水葡萄糖醇(1,5-AG)的变化情况,寻找早期葡萄糖代谢紊乱的筛查指标。 研究对467名体重正常和糖耐量正常的参与者(年龄范围:20-78岁)参加75g口

近日,国际杂志 《Diabetic Med》上在线发表一项关于糖耐量正常的中国人群中,血清1,5-脱水葡萄糖醇水平的降低与一级糖尿病家族史存在有关的研究。本研究旨在探讨中国糖尿病一级亲属(FDR)HbA 1c,糖化白蛋白(GA)和1,5-脱水葡萄糖醇(1,5-AG)的变化情况,寻找早期葡萄糖代谢紊乱的筛查指标。 研究对467名体重正常和糖耐量正常的参与者(年龄范围:20-78岁)参加75g口服葡萄糖耐量试验测定。用高效液相色谱法测定HbA 1c。血清GA和1,5-AG水平通过酶法测定。使用电化学发光免疫测定法测量血清胰岛素水平。 研究人群包括208名FDR和259名非FDR。FDR组血清1,5-AG水平低于非FDR组(20.4±7.5 vs 23.8±8.3μg/ ml,P < 0.001),HbA 1c和GA水平差异无统计学意义(P=0.835和0.469)。Logistic回归分析显示糖尿病一级家族史与血清1,5-AG水平降低(OR = 0.944,P < 0.001)有独立相关性。多元回归分析显示,糖尿病一级亲属史(β= -3.041,P <0.001)和胰岛素

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    2018-04-01 fengxx
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    2018-04-01 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-03-31 飛歌

    学习了很有用

    0

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