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NEJM:皮肤幼虫移行症-案例报道

2016-04-07 MedSci MedSci原创

男性,42岁,一个月前在尼日利亚度假后,发现右脚上开始出现强烈的瘙痒。据该患者主诉,皮肤瘙痒的部位呈迁移性的,每天瘙痒的范围会移动几毫米到几厘米之间。

男性,42岁,一个月前在尼日利亚度假后,发现右脚上开始出现强烈的瘙痒。

据该患者主诉,皮肤瘙痒的部位呈迁移性的,每天瘙痒的范围会移动几毫米到几厘米之间。

 
体格检查发现,右脚底部可见明显的匍匐形的,鼓起皮肤的条带(如图A和图B),这属于典型的爬行疹或皮肤幼虫移行症。

随后该病人遵医嘱应用阿苯达唑药物治疗2周后,病灶完全愈合。一个月后进行随访未见复发迹象。

皮肤幼虫移行症最典型的症状是引起迁移性的皮肤瘙痒,一般是通过接触受到感染的狗或猫粪便进行传播。感染到的幼虫因缺乏必要的胶原蛋白突破基底膜,从而被局限在表皮下,引起我们常见的红斑症状。

在临床上,它的特点是一种强烈的瘙痒、红斑、线性或匐行疹,最常见于足部、背部、臀部、大腿和腹部。

皮肤幼虫移行症是一种自限性疾病,临床上进行驱虫治疗通常可以减少症状和缩短病程。

原始出处:

Dong-Lai Ma, M.D., Ph.D.Sergio Vano-Galvan, M.D., Ph.D. Creeping Eruption — Cutaneous Larva MigransN Engl J Med 2016; 374:e16April 7, 2016


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  1. [GetPortalCommentsPageByObjectIdResponse(id=84450, encodeId=6165844500d, content=不错学到了新东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sat May 07 01:53:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78651, encodeId=2c7fe8651de, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Fri Apr 15 23:41:00 CST 2016, time=2016-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78289, encodeId=daa4e82895f, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78290, encodeId=48ebe829086, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76336, encodeId=3572e633669, content=曾在丹麦学习时见过一个孩子就是这样的表现,不过在我们科还没见过。学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Thu Apr 07 23:35:00 CST 2016, time=2016-04-07, status=1, ipAttribution=)]
    2016-05-07 1de4921fm57(暂无匿称)

    不错学到了新东西

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=84450, encodeId=6165844500d, content=不错学到了新东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sat May 07 01:53:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78651, encodeId=2c7fe8651de, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Fri Apr 15 23:41:00 CST 2016, time=2016-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78289, encodeId=daa4e82895f, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78290, encodeId=48ebe829086, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76336, encodeId=3572e633669, content=曾在丹麦学习时见过一个孩子就是这样的表现,不过在我们科还没见过。学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Thu Apr 07 23:35:00 CST 2016, time=2016-04-07, status=1, ipAttribution=)]
    2016-04-15 1de8e1afm39(暂无匿称)

    学习了,长知识了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=84450, encodeId=6165844500d, content=不错学到了新东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sat May 07 01:53:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78651, encodeId=2c7fe8651de, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Fri Apr 15 23:41:00 CST 2016, time=2016-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78289, encodeId=daa4e82895f, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78290, encodeId=48ebe829086, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76336, encodeId=3572e633669, content=曾在丹麦学习时见过一个孩子就是这样的表现,不过在我们科还没见过。学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Thu Apr 07 23:35:00 CST 2016, time=2016-04-07, status=1, ipAttribution=)]
    2016-04-14 李继凯

    文章不错

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=84450, encodeId=6165844500d, content=不错学到了新东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sat May 07 01:53:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78651, encodeId=2c7fe8651de, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Fri Apr 15 23:41:00 CST 2016, time=2016-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78289, encodeId=daa4e82895f, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78290, encodeId=48ebe829086, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76336, encodeId=3572e633669, content=曾在丹麦学习时见过一个孩子就是这样的表现,不过在我们科还没见过。学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Thu Apr 07 23:35:00 CST 2016, time=2016-04-07, status=1, ipAttribution=)]
    2016-04-14 李继凯

    值得关注

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=84450, encodeId=6165844500d, content=不错学到了新东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sat May 07 01:53:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78651, encodeId=2c7fe8651de, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Fri Apr 15 23:41:00 CST 2016, time=2016-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78289, encodeId=daa4e82895f, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78290, encodeId=48ebe829086, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:54:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76336, encodeId=3572e633669, content=曾在丹麦学习时见过一个孩子就是这样的表现,不过在我们科还没见过。学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Thu Apr 07 23:35:00 CST 2016, time=2016-04-07, status=1, ipAttribution=)]
    2016-04-07 layyjiangli

    曾在丹麦学习时见过一个孩子就是这样的表现,不过在我们科还没见过。学习了

    0

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