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J Affect Disord:研究揭示COPD患者呼吸困难和抑郁症状之间的关系

2018-07-27 MedSci MedSci原创

抑郁症是COPD的常见合并症,COPD症状,如呼吸困难可能在COPD与抑郁之间的因果关系中起重要作用。本研究中,我们探究了COPD患者呼吸困难和其他COPD参数和抑郁症状之间的相互关系。研究共纳入了 590例COPD患者。在3周住院肺康复的开始(T0)和结束(T1),呼吸困难方面强度(BORG量表),频率(2个CCQ项目),功能(CCQ-功能)和认知/情绪反应(2 SGRQ)项目)以及咳嗽(2个C

抑郁症是COPD的常见合并症,COPD症状,如呼吸困难可能在COPD与抑郁之间的因果关系中起重要作用。本研究中,我们探究了COPD患者呼吸困难和其他COPD参数和抑郁症状之间的相互关系。

研究共纳入了 590例COPD患者。在3周住院肺康复的开始(T0)和结束(T1),呼吸困难方面强度(BORG量表),频率(2个CCQ项目),功能(CCQ-功能)和认知/情绪反应(2 SGRQ)项目)以及咳嗽(2个CCQ项目),功能能力(6MWD),肺功能(FEV1)和抑郁症状(PHQ-9)进行了评估。使用PHQ-9总分作为因变量并使用PHQ-9单项的网络分析进行回归分析。检查了随时间的结构不变性。

结果显示,呼吸困难的频率,功能和认知/情绪反应与PHQ-9总分呈条件依赖关系。网络分析显示,呼吸困难频率和呼吸困难功能主要与躯体抑郁症状(例如,睡眠问题,能量损失)相关,而认知/情绪反应主要与认知-情感抑郁症状相关(例如,感觉沮丧/抑郁/绝望)。回归参数,网络结构和网络全局强度在T0和T1之间没有差异。

综上所述,该研究结果表明,呼吸困难和抑郁似乎与COPD患者的多种症状相关。结果可用于解释干预效应并制定新的干预策略以减少COPD的抑郁。

原始出处:

Schuler M, Wittmann M, et al., The interrelations among aspects of dyspnea and symptoms of depression in COPD patients-a network analysis. J Affect Disord. 2018 Jul 23;240:33-40. doi: 10.1016/j.jad.2018.07.021.

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    2018-10-13 cmsvly
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    2018-09-22 jyzxjiangqin

    研究揭示呼吸困难和抑郁之间的关系。

    0

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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Aug 29 21:21:01 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339174, encodeId=0b9b3391e4fe, content=抑郁症的原因和治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 17 20:30:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336637, encodeId=cd7d33663e7e, content=呼吸困难和抑郁症之间的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 05 12:45:54 CST 2018, time=2018-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335823, encodeId=f169335823e1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c53c2405614, createdName=汪海波, createdTime=Thu Aug 02 18:51:38 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281865, encodeId=e4761281865ed, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sun Jul 29 08:54:00 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2019-03-16 chenwq08
  5. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 05 12:45:54 CST 2018, time=2018-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335823, encodeId=f169335823e1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c53c2405614, createdName=汪海波, createdTime=Thu Aug 02 18:51:38 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281865, encodeId=e4761281865ed, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sun Jul 29 08:54:00 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-09-11 jyzxjiangqin

    呼吸困难和抑郁症之间的关系。

    0

  6. 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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sun Jul 29 08:54:00 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-08-29 jyzxjiangqin

    呼吸困难和抑郁症状。

    0

  7. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Aug 29 21:21:01 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339174, encodeId=0b9b3391e4fe, content=抑郁症的原因和治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 17 20:30:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336637, encodeId=cd7d33663e7e, content=呼吸困难和抑郁症之间的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 05 12:45:54 CST 2018, time=2018-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335823, encodeId=f169335823e1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c53c2405614, createdName=汪海波, createdTime=Thu Aug 02 18:51:38 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281865, encodeId=e4761281865ed, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sun Jul 29 08:54:00 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-08-17 jyzxjiangqin

    抑郁症的原因和治疗。

    0

  8. 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    2018-08-05 jyzxjiangqin

    呼吸困难和抑郁症之间的关系。

    0

  9. 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    2018-08-02 汪海波

    学习了

    0

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