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盘点:2018年6月9日Lancet研究精选

2018-06-08 zhangfan MedSci原创

2018年6月9日Lancet研究精选



【1】封面文章1--血管内超声肾神经切除术用于高血压治疗


近日研究人员考察了血管内超声肾神经切除术对高血压患者的治疗效果。RADIANCE-HTN SOLO研究招募18岁以上收缩期-舒张期高血压患者,患者血压135/85 mm Hg以上,药物治疗停止后4周血压170/105 mm Hg以下。患者随机接受肾神经切除术或模拟手术,研究的主要终点为日间动态收缩压的变化。146名患者参与研究,其中手术组74人,模拟组72人,手术后患者日间动态收缩压降低显著(8.5 vs 2.2 mmHg)。

【2】封面文章2--肾神经切除术联合药物治疗不受控制高血压


近日研究人员考察了肾神经切除术联合药物治疗对不受控制高血压患者血压的影响。收缩压150-180mmHg,舒张压>90mmH,24h动态收缩压140-170mmHg,服用1-3种降压药物的患者参与研究。89名患者参与研究,其中手术组38人,对照组42人。治疗6个月后,手术组血压较基线相比、门诊血压、24h收缩压、门诊舒张压以及24h舒张压的下降程度均优于对照组。24小时收缩压-舒张压时时变化显示,手术后血压呈持续性降低。

【3】达比加群可预防非心脏手术患者心肌损伤造成的血管并发症


抗凝血治疗可能预防非心脏手术后的心肌损伤(MINS)导致的心血管事件和死亡,近日研究人员评估了达比加群预防MINS患者主要血管并发症的效果。45岁以下,非心脏手术后发生心肌损伤且不超过35天的患者参与研究,其中877人服用达比加群,877人服用安慰剂,达比加群可降低主要血管并发症发病率(11% vs 15%)并且不会增加危及生命的严重或关键器官出血。

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    2018-08-10 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1829671, encodeId=021918296e140, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 10 23:36:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322798, encodeId=3f15322e9857, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7miblj4EHgFns3Mic85NWcRwwHYXCBDA8jW0GZ6iaZT55p0bicOcZXvsdT9henNafvCibicOUcwJtWUmkw/0, createdBy=a1fe1637734, createdName=wmw990556, createdTime=Sat Jun 09 11:53:07 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322613, encodeId=59f432261313, content=知之为知之, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Fri Jun 08 22:41:11 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322537, encodeId=8abf32253eec, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 08 15:03:15 CST 2018, time=2018-06-08, status=1, ipAttribution=)]
    2018-06-09 wmw990556

    学习

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1829671, encodeId=021918296e140, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 10 23:36:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322798, encodeId=3f15322e9857, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7miblj4EHgFns3Mic85NWcRwwHYXCBDA8jW0GZ6iaZT55p0bicOcZXvsdT9henNafvCibicOUcwJtWUmkw/0, createdBy=a1fe1637734, createdName=wmw990556, createdTime=Sat Jun 09 11:53:07 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322613, encodeId=59f432261313, content=知之为知之, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Fri Jun 08 22:41:11 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322537, encodeId=8abf32253eec, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 08 15:03:15 CST 2018, time=2018-06-08, status=1, ipAttribution=)]
    2018-06-08 易水河

    知之为知之

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1829671, encodeId=021918296e140, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 10 23:36:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322798, encodeId=3f15322e9857, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7miblj4EHgFns3Mic85NWcRwwHYXCBDA8jW0GZ6iaZT55p0bicOcZXvsdT9henNafvCibicOUcwJtWUmkw/0, createdBy=a1fe1637734, createdName=wmw990556, createdTime=Sat Jun 09 11:53:07 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322613, encodeId=59f432261313, content=知之为知之, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Fri Jun 08 22:41:11 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322537, encodeId=8abf32253eec, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 08 15:03:15 CST 2018, time=2018-06-08, status=1, ipAttribution=)]
    2018-06-08 龙胆草

    学习谢谢分享

    0

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