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赶快!数数你右边手臂有几颗痣?!赶快!

2015-10-22 MedSci MedSci原创

一项最新的研究表明:通过人们右手臂胎记和痣的数目可预测罹患黑色素瘤的风险。 小科普 黑色素瘤虽以“瘤”字结尾,但却是源于色素沉着区域的黑素细胞的恶性肿瘤。可通过血液和淋巴发生转移,恶性程度极高,可在诊断数月后死亡。但早期,非常表浅的病损5年治愈率可为100%。所以治愈率取决于早期诊断,早期治疗! 在美国,黑色素瘤在所有皮肤癌病例所占比例不到2%,但所导

一项最新的研究表明:通过人们右手臂胎记和痣的数目可预测罹患黑色素瘤的风险。

小科普



黑色素瘤虽以“瘤”字结尾,但却是源于色素沉着区域的黑素细胞的恶性肿瘤。可通过血液和淋巴发生转移,恶性程度极高,可在诊断数月后死亡。但早期,非常表浅的病损5年治愈率可为100%。所以治愈率取决于早期诊断,早期治疗!

在美国,黑色素瘤在所有皮肤癌病例所占比例不到2%,但所导致的患者死亡率极高。今年,美国新发73000多名黑色素瘤患者,预计近1万名患者将死于黑色素瘤。 

相关研究

这项最新的研究由英国伦敦国王学院Simon Ribero领导的团队进行,研究于近期发表在British Journal of Dermatology。 

研究对象为1995年1月到2003年12月的3594名白人双胞胎女性。经过培训的护士对参与者17个身体区域的痣的数目进行了统计。然后研究人员在另一项小规模研究中对400名男性和女性进行了同样的痣的数目统计。

研究结果

人们右手臂色素痣的数量是统计全身痣数量的强烈预测因子。



若女性右臂的痣超过7个,则有高出9倍的可能性(相比没有这么多痣的人),全身痣的总数会超过50个(OR:8.81;CI:7.03-11.04);

若女性右臂的痣超过11个,则有高出9倍的可能性,全身痣的总数超出100个(OR:9.38,95%CI:6.71-13.11)。

预示她们患黑色素瘤的风险是常人的5倍。

此前在澳大利亚进行的一项研究显示,手臂上超过10颗痣意味着罹患黑色素瘤的风险增加11倍!

研究评论

1.英国癌症研究中心,Dr Claire Knight说:“这项研究说明,在我们手臂上的色素痣的总数可以推算出全身色素痣总数。这一点对于那些高黑色素瘤风险的人群是有帮助的。”她提醒人们不能只能关注手臂,而忽略身体其它部位。“只有少于一半的黑色素瘤从已有的色素痣发展而来,所以检查全身皮肤色素痣是否正常很重要,告诉医生关于它的任何变化,包括大小、形状、颜色或感觉或原有的正常斑块。不能仅仅关注手臂,色素瘤可以从身体任何部位发出,最常见于男性躯干和女性的腿部。”

2.Ribero博士认为“胎记或痣是导致民众患黑色素瘤的高危风险因素,若一个人的胎记或痣越多,则其患黑色素瘤的风险越大。通过计数人们右手臂的痣的数目预计全身痣的数目,这种方法可有效估计人们患黑色素瘤的风险,并可及时有效做出防范措施和风险筛查。”

研究的局限

1.该研究只能显示两个因素的潜在关系,但不能显示因果关系。

2.研究只对几个可调控的变量进行了研究,如年龄、身高和皮肤类型,但仍有其他一些因素需要调整,如个体对太阳的暴露,是否经常涂防晒霜和是否有激素变化。



3.研究的结果暂不能完全适用于男性或非白人女性。

MedSci小编提示:

以下危险信号提示色素痣恶变:大小改变、颜色改变,变红、变白、变蓝,特别是色素沉着区向周围正常皮肤扩散;表面特征改变,质地形状的改变;尤其是痣周围皮肤出现炎症反应,可能有出血,溃疡,瘙痒或疼痛等表现。

其它黑色素瘤风险因子包括红色或浅色的头发,浅色皮肤,浅色眼睛或有晒伤史。



1.如果你发现皮肤上的小斑块在最近几周或几个月里发生了变化,一定要去看医生。

2.虽然不能控制色素痣的数量,但为了预防皮肤癌一定要避免过度的阳光直射。

3.高防晒系数(SPF)的防晒霜有很好的预防作用。不建议使用紫外线灯和日光浴浴床来达到改变皮肤颜色的作用。普通的棕褐色比较安全。



4.对皮肤上已存在的色素痣的性状的改变也要引起重视。

看了以上内容还不赶紧数数右边手臂有几颗痣?虽然不能完全预测罹患皮肤癌的风险,但皮肤痣的数量和黑色素瘤的风险相关性很强哦,已经过多个研究验证。没事儿,多照照镜子看看身体的变化吧!(不穿衣服哦)



参考文献:


Ribero S, Zugna D, Osella-Abate S, Glass D, Nathan P, Spector T, Bataille V.Prediction of high naevus count in a healthy uk population to estimate melanoma risk.Br J Dermatol. 2015 Oct 19. 


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  1. [GetPortalCommentsPageByObjectIdResponse(id=61664, encodeId=452f61664bb, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:56:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40538, encodeId=3752405385d, content=数数, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLD1O97y3am76k8v12uX92l8MnMUZBZIrorphCDWyEYgqDulOfDXQZLWGiaSibbvm6F0ficxxxDMzwY9g/132, createdBy=bae077124, createdName=Jin Chou, createdTime=Sat Oct 24 06:49:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487613, encodeId=b87d148e613c1, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Sat Oct 24 06:16:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40422, encodeId=ff3f4042296, content=有点意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150925/IMG560509F273F627198.jpg, createdBy=6dc51652582, createdName=chucklehead, createdTime=Fri Oct 23 12:56:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40365, encodeId=97b840365d7, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Fri Oct 23 07:38:00 CST 2015, time=2015-10-23, status=1, ipAttribution=)]
    2016-01-28 Wuyue6233

    有趣

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=61664, encodeId=452f61664bb, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:56:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40538, encodeId=3752405385d, content=数数, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLD1O97y3am76k8v12uX92l8MnMUZBZIrorphCDWyEYgqDulOfDXQZLWGiaSibbvm6F0ficxxxDMzwY9g/132, createdBy=bae077124, createdName=Jin Chou, createdTime=Sat Oct 24 06:49:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487613, encodeId=b87d148e613c1, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Sat Oct 24 06:16:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40422, encodeId=ff3f4042296, content=有点意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150925/IMG560509F273F627198.jpg, createdBy=6dc51652582, createdName=chucklehead, createdTime=Fri Oct 23 12:56:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40365, encodeId=97b840365d7, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Fri Oct 23 07:38:00 CST 2015, time=2015-10-23, status=1, ipAttribution=)]
    2015-10-24 Jin Chou

    数数

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=61664, encodeId=452f61664bb, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:56:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40538, encodeId=3752405385d, content=数数, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLD1O97y3am76k8v12uX92l8MnMUZBZIrorphCDWyEYgqDulOfDXQZLWGiaSibbvm6F0ficxxxDMzwY9g/132, createdBy=bae077124, createdName=Jin Chou, createdTime=Sat Oct 24 06:49:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487613, encodeId=b87d148e613c1, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Sat Oct 24 06:16:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40422, encodeId=ff3f4042296, content=有点意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150925/IMG560509F273F627198.jpg, createdBy=6dc51652582, createdName=chucklehead, createdTime=Fri Oct 23 12:56:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40365, encodeId=97b840365d7, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Fri Oct 23 07:38:00 CST 2015, time=2015-10-23, status=1, ipAttribution=)]
    2015-10-24 yese
  4. [GetPortalCommentsPageByObjectIdResponse(id=61664, encodeId=452f61664bb, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:56:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40538, encodeId=3752405385d, content=数数, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLD1O97y3am76k8v12uX92l8MnMUZBZIrorphCDWyEYgqDulOfDXQZLWGiaSibbvm6F0ficxxxDMzwY9g/132, createdBy=bae077124, createdName=Jin Chou, createdTime=Sat Oct 24 06:49:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487613, encodeId=b87d148e613c1, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Sat Oct 24 06:16:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40422, encodeId=ff3f4042296, content=有点意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150925/IMG560509F273F627198.jpg, createdBy=6dc51652582, createdName=chucklehead, createdTime=Fri Oct 23 12:56:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40365, encodeId=97b840365d7, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Fri Oct 23 07:38:00 CST 2015, time=2015-10-23, status=1, ipAttribution=)]
    2015-10-23 chucklehead

    有点意思

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=61664, encodeId=452f61664bb, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:56:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40538, encodeId=3752405385d, content=数数, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLD1O97y3am76k8v12uX92l8MnMUZBZIrorphCDWyEYgqDulOfDXQZLWGiaSibbvm6F0ficxxxDMzwY9g/132, createdBy=bae077124, createdName=Jin Chou, createdTime=Sat Oct 24 06:49:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487613, encodeId=b87d148e613c1, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Sat Oct 24 06:16:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40422, encodeId=ff3f4042296, content=有点意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150925/IMG560509F273F627198.jpg, createdBy=6dc51652582, createdName=chucklehead, createdTime=Fri Oct 23 12:56:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40365, encodeId=97b840365d7, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Fri Oct 23 07:38:00 CST 2015, time=2015-10-23, status=1, ipAttribution=)]
    2015-10-23 Guoxj3234

    有趣

    0

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