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SCI REP:比较原发性醛固酮增多症患者和原发性高血压患者微血管和大血管的变化!

2017-06-02 xing.T MedSci原创

总之,原发性醛固酮增多症患者相比于原发性高血压患者AVR发生了显著的改变,它可以代表微血管重塑的一个早期和更可靠的指标。

近日,Scientific reports 杂志上发表了一篇研究文章,研究人员通过一项病例对照研究来评估原发性醛固酮增多症患者、原发性高血压患者和健康受试者他们的大血管和微血管的变化情况。

研究人员采用评估动脉硬化程度的指标包括采用TensioClinic动脉造影系统评估的增强指数和脉搏波传导速度。视网膜微循环是通过视网膜血管成像仪(RVA)和非Midriatic相机(Topcon-TRC-NV2000)来进行拍照。IMEDOS软件被用来分析视网膜动脉直径(RAD),视网膜静脉直径(RVD)和视盘血管的动脉静脉比(AVR)。

研究人员分别招募了30名原发性醛固酮增多症患者、39名原发性高血压患者和35名健康受试者。原发性醛固酮增多症患者只有与对照者相比才表现出较高的脉搏波传导速度。平均肱动脉和主动脉增强指数在各组间的差异无统计学意义。在原发性醛固酮增多症患者中,平均RVD和AVR值要明显低于原发性高血压患者和健康对照者,而这些参数在原发性高血压者与健康对照者之间没有显著差异。

总之,原发性醛固酮增多症患者相比于原发性高血压患者AVR发生了显著的改变,它可以代表微血管重塑的一个早期和更可靠的指标。

原始出处:

Monica Varano,et al. Comparisons of microvascular and macrovascular changes in aldosteronism-related hypertension and essential hypertension. Scientific reports. 2017. https://www.nature.com/articles/s41598-017-02622-2

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    2022-12-28 delianjihui 来自新疆

    重视原醛的诊断筛查

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    2022-12-28 delianjihui 来自新疆

    转发学习

    0

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    2022-12-28 delianjihui 来自新疆

    感谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2107900, encodeId=ca80210e90016, content=重视原醛的诊断筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:31:16 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107898, encodeId=939e210e898a2, content=转发学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:32 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107897, encodeId=761d210e89702, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:26 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107896, encodeId=f278210e8962a, content=学习受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:08 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2043204, encodeId=89b52043204c5, content=<a href='/topic/show?id=c1e83e138a7' target=_blank style='color:#2F92EE;'>#原发性高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37138, encryptionId=c1e83e138a7, topicName=原发性高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Wed Apr 11 23:53:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080060, encodeId=417a208006016, content=<a href='/topic/show?id=5efa956449d' target=_blank style='color:#2F92EE;'>#醛固酮增多症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95644, encryptionId=5efa956449d, topicName=醛固酮增多症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7b6284, createdName=FukaiBao, createdTime=Mon Jul 03 19:53:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706110, encodeId=1e521e06110d9, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Fri Oct 20 09:53:00 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846551, encodeId=3782184655179, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Mon Oct 16 03:53:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365313, encodeId=d84f136531319, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379216, encodeId=e96e13e9216e9, content=<a href='/topic/show?id=ac549564240' target=_blank style='color:#2F92EE;'>#醛固酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95642, encryptionId=ac549564240, topicName=醛固酮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2022-12-28 delianjihui 来自新疆

    学习受益

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=2107900, encodeId=ca80210e90016, content=重视原醛的诊断筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:31:16 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107898, encodeId=939e210e898a2, content=转发学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:32 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107897, encodeId=761d210e89702, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:26 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107896, encodeId=f278210e8962a, content=学习受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:08 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2043204, encodeId=89b52043204c5, content=<a href='/topic/show?id=c1e83e138a7' target=_blank style='color:#2F92EE;'>#原发性高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37138, encryptionId=c1e83e138a7, topicName=原发性高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Wed Apr 11 23:53:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080060, encodeId=417a208006016, content=<a href='/topic/show?id=5efa956449d' target=_blank style='color:#2F92EE;'>#醛固酮增多症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95644, encryptionId=5efa956449d, topicName=醛固酮增多症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7b6284, createdName=FukaiBao, createdTime=Mon Jul 03 19:53:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706110, encodeId=1e521e06110d9, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Fri Oct 20 09:53:00 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846551, encodeId=3782184655179, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Mon Oct 16 03:53:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365313, encodeId=d84f136531319, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379216, encodeId=e96e13e9216e9, content=<a href='/topic/show?id=ac549564240' target=_blank style='color:#2F92EE;'>#醛固酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95642, encryptionId=ac549564240, topicName=醛固酮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
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    2017-10-20 kkunny
  8. [GetPortalCommentsPageByObjectIdResponse(id=2107900, encodeId=ca80210e90016, content=重视原醛的诊断筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:31:16 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107898, encodeId=939e210e898a2, content=转发学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:32 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107897, encodeId=761d210e89702, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:26 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107896, encodeId=f278210e8962a, content=学习受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:08 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2043204, encodeId=89b52043204c5, content=<a href='/topic/show?id=c1e83e138a7' target=_blank style='color:#2F92EE;'>#原发性高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37138, encryptionId=c1e83e138a7, topicName=原发性高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Wed Apr 11 23:53:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080060, encodeId=417a208006016, content=<a href='/topic/show?id=5efa956449d' target=_blank style='color:#2F92EE;'>#醛固酮增多症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95644, encryptionId=5efa956449d, topicName=醛固酮增多症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7b6284, createdName=FukaiBao, createdTime=Mon Jul 03 19:53:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706110, encodeId=1e521e06110d9, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Fri Oct 20 09:53:00 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846551, encodeId=3782184655179, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Mon Oct 16 03:53:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365313, encodeId=d84f136531319, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379216, encodeId=e96e13e9216e9, content=<a href='/topic/show?id=ac549564240' target=_blank style='color:#2F92EE;'>#醛固酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95642, encryptionId=ac549564240, topicName=醛固酮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=2107900, encodeId=ca80210e90016, content=重视原醛的诊断筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:31:16 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107898, encodeId=939e210e898a2, content=转发学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:32 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107897, encodeId=761d210e89702, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:26 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107896, encodeId=f278210e8962a, content=学习受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:08 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2043204, encodeId=89b52043204c5, content=<a href='/topic/show?id=c1e83e138a7' target=_blank style='color:#2F92EE;'>#原发性高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37138, encryptionId=c1e83e138a7, topicName=原发性高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Wed Apr 11 23:53:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080060, encodeId=417a208006016, content=<a href='/topic/show?id=5efa956449d' target=_blank style='color:#2F92EE;'>#醛固酮增多症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95644, encryptionId=5efa956449d, topicName=醛固酮增多症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7b6284, createdName=FukaiBao, createdTime=Mon Jul 03 19:53:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706110, encodeId=1e521e06110d9, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Fri Oct 20 09:53:00 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846551, encodeId=3782184655179, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Mon Oct 16 03:53:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365313, encodeId=d84f136531319, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379216, encodeId=e96e13e9216e9, content=<a href='/topic/show?id=ac549564240' target=_blank style='color:#2F92EE;'>#醛固酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95642, encryptionId=ac549564240, topicName=醛固酮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-03 mgqwxj
  10. [GetPortalCommentsPageByObjectIdResponse(id=2107900, encodeId=ca80210e90016, content=重视原醛的诊断筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:31:16 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107898, encodeId=939e210e898a2, content=转发学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:32 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107897, encodeId=761d210e89702, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:26 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2107896, encodeId=f278210e8962a, content=学习受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5281475204, createdName=delianjihui, createdTime=Wed Dec 28 20:30:08 CST 2022, time=2022-12-28, status=1, ipAttribution=新疆), GetPortalCommentsPageByObjectIdResponse(id=2043204, encodeId=89b52043204c5, content=<a href='/topic/show?id=c1e83e138a7' target=_blank style='color:#2F92EE;'>#原发性高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37138, encryptionId=c1e83e138a7, topicName=原发性高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Wed Apr 11 23:53:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080060, encodeId=417a208006016, content=<a href='/topic/show?id=5efa956449d' target=_blank style='color:#2F92EE;'>#醛固酮增多症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95644, encryptionId=5efa956449d, topicName=醛固酮增多症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7b6284, createdName=FukaiBao, createdTime=Mon Jul 03 19:53:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706110, encodeId=1e521e06110d9, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Fri Oct 20 09:53:00 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846551, encodeId=3782184655179, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Mon Oct 16 03:53:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365313, encodeId=d84f136531319, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379216, encodeId=e96e13e9216e9, content=<a href='/topic/show?id=ac549564240' target=_blank style='color:#2F92EE;'>#醛固酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95642, encryptionId=ac549564240, topicName=醛固酮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sat Jun 03 23:53:00 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-03 cmsvly

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最近的研究数据表明,有高血压的人与非高血压人群相比,可能不会增加原发性醛固酮增多症风险;不过,顽固性高血压患者应筛查原发性醛固酮增多症。 来自纽约西奈山医学院糖尿病和骨疾病的Khadeen Christi Cheesman博士和同事对296名成年高血压患者的数据进行了评估。 根据血浆醛固酮浓度和醛固酮肾素比,选出了14名可能患有原发性醛固酮增多症的患者,初始测试率为4.7%。这些患者中

J Hypertens:原发性醛固酮增多症患者血浆中半乳糖凝集素-3的意义!

原发性醛固酮增多症患者血浆Gal-3浓度相比于原发性高血压患者并不升高,并且其水平在肾上腺切除后并不降低。这些结果与以前的研究不一致,并不支持在原发性醛固酮增多症患者血浆中Gal-3在心血管疾病风险增加中的病理生理作用。

Lancet Diabetes Endo:单侧肾上腺切除的原发性醛固酮增多症效果评价

大多数患者从肾上腺切除术中获益,年轻患者和女性患者更容易获得良好的手术结果

J Hypertens:原发性醛固酮增多症患者新发糖尿病的风险如何?

由此可见,原发性醛固酮增多症患者行肾上腺切除术降低了NODM的发生和全因死亡率的风险,与匹配的高血压对照者相比。这一观察结果增加了更多的证据来表明原发性醛固酮增多症与较高的代谢综合征和长期死亡率风险相关。

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