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BMJ:肥胖是癌症第二大可控危险因素,与11种癌症有关!

2017-03-15 朱柳媛 中国循环杂志

BMJ刊文称,肥胖是癌症的第二大可控危险因素,与11种癌症有关



近期,BMJ刊登的一篇综述表明,肥胖与11种肿瘤有关,其中大多数是消化道肿瘤和女性激素相关的肿瘤,包括食管腺癌、多发性骨髓瘤、胃底贲门癌、结肠癌(男性)、直肠癌(男性)、胆管系统癌症、胰腺癌乳腺癌(绝经后女性)、子宫内膜癌(绝经前女性)、卵巢癌及肾癌。

研究者还发现,体重指数每增加5 kg/m2,上述各种不同癌症的风险存在较大差异:男性直肠癌风险增加9%,而胆管系统癌症风险可增加56%。

相关述评认为,这与国际癌症研究机构(IARC)去年报告的大部分一样,不过IARC认为肥胖还与肝癌、甲状腺癌有关。

研究者指出,肥胖应该是继吸烟后的第二大可控癌症危险因素。

这一综述初筛了95项Meta分析结果,但最终仅对其中12项有强烈证据的分析进行了评估。

原始出处:

Maria Kyrgiou,Ilkka Kalliala,Georgios Markozannes,et al.Adiposity and cancer at major anatomical sites: umbrella review of theliterature. BMJ.2017 Feb 28;356:j477

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1848254, encodeId=75401848254ee, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Sep 10 06:55:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180875, encodeId=a2021808e533, content=了解肥胖最新进展,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/1A51842815047D40BFDAA8D69AA8E519/100, createdBy=fd7f2029163, createdName=绛珠草小姐, createdTime=Sat Mar 18 12:40:03 CST 2017, time=2017-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180104, encodeId=4f3718010416, content= 研究者指出,肥胖应该是继吸烟后的第二大可控癌症危险因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Wed Mar 15 15:10:36 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180099, encodeId=f46e18009939, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:42:00 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-09-10 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1848254, encodeId=75401848254ee, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Sep 10 06:55:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180875, encodeId=a2021808e533, content=了解肥胖最新进展,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/1A51842815047D40BFDAA8D69AA8E519/100, createdBy=fd7f2029163, createdName=绛珠草小姐, createdTime=Sat Mar 18 12:40:03 CST 2017, time=2017-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180104, encodeId=4f3718010416, content= 研究者指出,肥胖应该是继吸烟后的第二大可控癌症危险因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Wed Mar 15 15:10:36 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180099, encodeId=f46e18009939, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:42:00 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-03-18 绛珠草小姐

    了解肥胖最新进展,谢谢分享

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1848254, encodeId=75401848254ee, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Sep 10 06:55:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180875, encodeId=a2021808e533, content=了解肥胖最新进展,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/1A51842815047D40BFDAA8D69AA8E519/100, createdBy=fd7f2029163, createdName=绛珠草小姐, createdTime=Sat Mar 18 12:40:03 CST 2017, time=2017-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180104, encodeId=4f3718010416, content= 研究者指出,肥胖应该是继吸烟后的第二大可控癌症危险因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Wed Mar 15 15:10:36 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180099, encodeId=f46e18009939, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:42:00 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-03-15 knowheart

    研究者指出,肥胖应该是继吸烟后的第二大可控癌症危险因素。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1848254, encodeId=75401848254ee, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Sep 10 06:55:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180875, encodeId=a2021808e533, content=了解肥胖最新进展,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/1A51842815047D40BFDAA8D69AA8E519/100, createdBy=fd7f2029163, createdName=绛珠草小姐, createdTime=Sat Mar 18 12:40:03 CST 2017, time=2017-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180104, encodeId=4f3718010416, content= 研究者指出,肥胖应该是继吸烟后的第二大可控癌症危险因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Wed Mar 15 15:10:36 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180099, encodeId=f46e18009939, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:42:00 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-03-15 Chongyang Zhang

    签到学习了很多。

    0

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