Invest Radiol：多次大环对比剂（钆布醇）增强造影后是否会产生钆剂沉积？

2017-09-03 shaosai MedSci原创

钆布醇作为一种广泛使用的大环对比剂，是否会在行多次对比增强后有钆剂沉积尚具有争议性。本研究旨在验证由于钆剂的沉积，是否多次行钆布醇增强检查会引起平扫T1WI图像上齿状核（DN）和苍白球（GP）信号的增高，并将结果发表在Invest Radiol上。

钆布醇作为一种广泛使用的大环对比剂，是否会在行多次对比增强后有钆剂沉积尚具有争议性。本研究旨在验证由于钆剂的沉积，是否多次行钆布醇增强检查会引起平扫T1WI图像上齿状核（DN）和苍白球（GP）信号的增高，并将结果发表在Invest Radiol上。本研究共纳入了自2009年8月-2016年8月的189例至少进行2次钆布醇对比剂增强MR检查的患者。通过剪影首次MR图像和最后一次MR图像来计算T1WI平扫图像上DN/脑桥和GP/丘脑的信号强度（SI）比的差异。单样本T检验来评价SI比值与0的差异。显影回归和Pearson相关性分析用来评价SI比值间的差异和各种混杂变量，例如扫描次数、扫描间歇时间、年龄、性别、放化疗史和肝肾功能。结果为，所有受试者平均行增强对比MR次数为5.9 ± 6.3，检查间隔平均为42.8 ± 49.5周。63例患者检查次数为6次以上，126例患者扫描次数低于6次。DN/脑桥和GP/丘脑的SI比与0比较均无显着性差异，平均值分别为-0.012 ± 0.115 (P = 0.148)、0.012 ± 0.111 (P = 0.126)。本研究表明，多次行钆布醇造影剂检查

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2018-02-13 ms1692810954239974

#钆剂#

79 0
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2018-04-02 xiangyuzhou971

#EST#

57 0
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2017-09-05 sodoo

#造影#

50 0
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2017-09-04 shaosai

好好学习.涨知识

89 0
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2017-09-03 184****9840

学习了谢谢分享

92 0
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2017-09-03 tanxingdoctor

学习啦学习啦!谢谢分享!

0 0
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2017-09-03 中医痴

不错的.学习了.谢谢分享!

102 0
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2017-09-03 明心见性

学习了.谢谢分享

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