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Scand J of Gastroenterol:乳糜泻被误诊为肠易激综合征的问题

2013-07-11 吴军 编译 cmt

现已知乳糜泻能呈现肠易激综合征(IBS)特点的临床症状,并且在胃肠病科就诊的患者中,很大一部分有这些症状的患者可能有乳糜泻。 来自英国的Timothy Card医生调查了关于乳糜泻被误诊为肠易激综合征的普遍程度,以及误诊是否延迟了正确的诊断。[Scand J of Gastroenterol 2013: 48(7) :801-807] 研究者使用来自英国综合医疗研究

现已知乳糜泻能呈现肠易激综合征(IBS)特点的临床症状,并且在胃肠病科就诊的患者中,很大一部分有这些症状的患者可能有乳糜泻。

来自英国的Timothy Card医生调查了关于乳糜泻被误诊为肠易激综合征的普遍程度,以及误诊是否延迟了正确的诊断。[Scand J of Gastroenterol 2013: 48(7) :801-807]

研究者使用来自英国综合医疗研究数据库(GPRD)的电脑记录,进行了一项病例对照研究。

研究者比较了乳糜泻患者之前诊断为IBS或在正确诊断为乳糜泻之前,因IBS接受一段时间治疗的比例。

研究者以既往有类似诊断或治疗的无乳糜泻患者作为对照组。

医生检查发现,与5%的对照组相比,实验组16%的乳糜泻患者有优先诊断IBS。

当研究者考虑IBS的典型治疗方法而不是诊断时,28%的乳糜泻患者显示呈被治疗,而对照组只有9%。

在诊断乳糜泻之前,许多IBS的诊断出现在去年;但即使在10年前,也存在明显的IBS过度诊疗。

Card医生的团队评论指出,“在当代的英国临床诊疗中,可能存在至少1个乳糜泻患者被耗费多年时间接受IBS的治疗。”

“接下来的指南关于应用血清学检测乳糜泻将会减少这些问题”。


An excess of prior irritable bowel syndrome diagnoses or treatments in Celiac disease: evidence of diagnostic delay  

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    2014-02-27 许安
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