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Am J cardiol:PPCI后复发性心梗显著影响患者转归

2013-11-07 高晓方 译 医学论坛网

荷兰一项研究表明,在当前临床实践中,直接经皮冠状动脉介入(PPCI)后复发性心梗仍为相对常见并发症,并且可显著升高死亡、卒中和出血风险。论文11月4日在线发表于《美国心脏病学杂志》(Am J cardiol)。 此项研究共纳入1700例接受PPCI和支架置入的ST段抬高心肌梗死患者,并评估了复发性心梗对后续临床转归的影响。在中位随访4.7年间,共有240例患者出现复发性心

荷兰一项研究表明,在当前临床实践中,直接经皮冠状动脉介入(PPCI)后复发性心梗仍为相对常见并发症,并且可显著升高死亡、卒中和出血风险。论文11月4日在线发表于《美国心脏病学杂志》(Am J cardiol)。


此项研究共纳入1700例接受PPCI和支架置入的ST段抬高心肌梗死患者,并评估了复发性心梗对后续临床转归的影响。在中位随访4.7年间,共有240例患者出现复发性心梗。

结果显示,复发性心梗与后续心源性死亡(危险比[HR] 6.86)、非心源性死亡(HR 2.02)、卒中(HR 3.68)和中重度出血(HR 3.71)风险升高具有相关性。早期复发性心梗(PPCI实施1日内)与未校正心源性死亡率升高具有相关性。进行多变量校正之后,晚期复发性心梗(PPCI实施1年后)与后续心源性死亡风险最高具有相关性。心源性死亡风险与复发性心梗期间是否存在持续ST段抬高无关。

原文出处:

Kikkert WJ, Hoebers LP, Damman P, Lieve KV, Claessen BE, Vis MM, Baan J Jr, Koch KT, de Winter RJ, Piek JJ, Tijssen JG, Henriques JP.Recurrent Myocardial Infarction After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction.Am J Cardiol. 2013 Oct 3. pii: S0002-9149(13)01929-2. doi: 10.1016/j.amjcard.2013.08.039. 

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