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澳科学家找到杀灭超级细菌新方法

2018-03-07 新华网 新华网

澳大利亚阿德莱德大学6日宣布,该校研究人员找到了一种杀灭超级细菌的新方法,即通过改变铁供应使其变弱甚至死亡。超级细菌指对多种抗生素都有耐药性的细菌,由于病人感染超级细菌后缺乏有效治疗药物,有估计认为它们每年致死70万人。世界卫生组织预计,到2050年这一数字可能达1000万。因此,应对超级细菌成为医学界的紧迫任务。阿德莱德大学研究人员凯塔琳娜·里奇特在该校发布的新闻公报中说,她在研究中针对超级细菌

澳大利亚阿德莱德大学6日宣布,该校研究人员找到了一种杀灭超级细菌的新方法,即通过改变铁供应使其变弱甚至死亡。超级细菌指对多种抗生素都有耐药性的细菌,由于病人感染超级细菌后缺乏有效治疗药物,有估计认为它们每年致死70万人。世界卫生组织预计,到2050年这一数字可能达1000万。因此,应对超级细菌成为医学界的紧迫任务。

katharina-richter.jpg

阿德莱德大学研究人员凯塔琳娜·里奇特在该校发布的新闻公报中说,她在研究中针对超级细菌的噬铁特性,改变超级细菌的铁供应,使它们丧失致病功能,最终死亡。

“铁对细菌而言就像是巧克力,带给细菌能量,让它们不断长大、致病,并能抵抗人类免疫系统和抗生素的攻击。”里奇特说,通过使用两种不同的化合物,我们先是让细菌缺铁,进而喂给它们对细菌而言有毒的物质,饥饿的细菌对这些有毒物质毫无抵抗力。

GoldenStaph_KR-300x202.jpg

这种方法已经在动物实验中证明对金黄色葡萄球菌等超级细菌有效,下一步将运用到治疗鼻窦感染的人体试验中。两种化合物被包含在啫喱状物质中,可以只用于感染部位而无需全身施药。

里奇特表示,目前没有发现这种疗法有副作用,而且细菌在这种疗法下出现耐药性的风险也较低,因为细菌不大可能抗拒自己喜欢的食物。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1903313, encodeId=ebf31903313e2, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Mar 10 20:30:00 CST 2018, time=2018-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307182, encodeId=b7c730e182cf, content=非常好.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cee2018203, createdName=1e207054m17(暂无匿称), createdTime=Thu Apr 19 07:14:52 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321693, encodeId=dabb1321693fa, content=<a href='/topic/show?id=64049291048' target=_blank style='color:#2F92EE;'>#超级细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92910, encryptionId=64049291048, topicName=超级细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea13490, createdName=xqptu, createdTime=Fri Mar 09 05:30:00 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293871, encodeId=2cb32938e1a7, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Mar 07 15:45:33 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293854, encodeId=d952293854cb, content=好好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Wed Mar 07 15:04:59 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293848, encodeId=a002293848d3, content=好文章.学习;了, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed Mar 07 14:34:55 CST 2018, time=2018-03-07, status=1, ipAttribution=)]
    2018-04-19 1e207054m17(暂无匿称)

    非常好.谢谢分享

    0

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    2018-03-07 131****1460

    学习了受益匪浅

    0

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    2018-03-07 忠诚向上

    好好好学习天天向上

    0

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    2018-03-07 1e0f8808m18(暂无匿称)

    好文章.学习;了

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