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Diabetes Care:低葡萄糖负荷(GL)加菜籽油饮食能显著控制2型糖尿病患者血糖及心血管风险控制

2014-06-19 MedSci MedSci原创

为期3个月,以全麦饮食作为对照,观察低葡萄糖负荷(GL)加菜籽油(31g/2000千卡)饮食,对2型糖尿病患者血糖控制(HbA1c) 和心血管危险因素(LDL-C和TG)的效果,结果表明,与对照组相比,该饮食显著改善了血糖控制,并降低了Framingham心脏风险评分。这是一项平行,随机对照的为期3个月治疗,研究纳入141名T2DM患者,经口服降糖药后HbA1c在6.5%-8.5% [48-69

为期3个月,以全麦饮食作为对照,观察低葡萄糖负荷(GL)加菜籽油(31g/2000千卡)饮食,对2型糖尿病患者血糖控制(HbA1c) 和心血管危险因素(LDL-C和TG)的效果,结果表明,与对照组相比,该饮食显著改善了血糖控制,并降低了Framingham心脏风险评分。

这是一项平行,随机对照的为期3个月治疗,研究纳入141名T2DM患者,经口服降糖药后HbA1c在6.5%-8.5% [48-69 mmol/mol]之间。这些患者经过低葡萄糖负荷(GL)加菜籽油饮食(31 g菜籽油约2000卡热量)与全谷饮食进行对比。主要终点为HbA1c的变化,次要终点为Framingham 心血管评分,以及reactive hyperemia index率。

结果表明,试验组79%人群,对照组90%人完成试验。试验组人群HbA1c减少-0.47% (-5.15 mmol/mol) (95% CI -0.54% to -0.40% [-5.92 to -4.38 mmol/mol]),明显优于对照组-0.31% [-3.44 mmol/mol] [95% CI -0.38% to -0.25% (-4.17 to -2.71 mmol/mol),p=0.002。尤其是收缩压高的人群。同时,心血管风险评分以及RHI率也显著下降。这些结果表明,低葡萄糖负荷(GL)加菜籽油饮食能显著控制2型糖尿病患者血糖及心血管风险控制。

原始出处:


Jenkins DJ, Kendall CW, Vuksan V, Faulkner D, Augustin LS, Mitchell S, Ireland C, Srichaikul K, Mirrahimi A, Chiavaroli L, Blanco Mejia S, Nishi S, Sahye-Pudaruth S, Patel D, Bashyam B, Vidgen E, de Souza RJ, Sievenpiper JL, Coveney J, Josse RG, Leiter LA.Effect of Lowering the Glycemic Load With Canola Oil on Glycemic Control and Cardiovascular Risk Factors: A Randomized Controlled Trial.Diabetes Care. 2014 Jun 14. pii: DC_132990.【下载链接】

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    2017-12-08 wl1122050

    菜籽油到底他问@么了?

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createdName=xue8604, createdTime=Sat Jun 21 12:59:00 CST 2014, time=2014-06-21, status=1, ipAttribution=)]
    2015-04-11 x35042875

    国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间

    0

  5. 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  6. 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createdName=xue8604, createdTime=Sat Jun 21 12:59:00 CST 2014, time=2014-06-21, status=1, ipAttribution=)]
    2015-05-01 智智灵药
  7. 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