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AJKD:地中海饮食不能改善心血管疾病高危老年人肾功能

2012-09-04 范振光 文献宝贝

  当前的流行病学调查观察已经发现了健康的饮食结构成分可以改善人们的肾功能。     《美国肾脏病杂志》(Am J Kidney Dis. 2012 Sep;60(3):380-9.)上的一项研究评估了地中海饮食(MedDiet)对肾脏功能的影响,数据来自关于MedDiet饮食对原发性心血管疾病的干预效果的PREDIMED研究,该研究来自多中心的3个随机临床研究,采取横断面评估和1年

  当前的流行病学调查观察已经发现了健康的饮食结构成分可以改善人们的肾功能。
 
  《美国肾脏病杂志》(Am J Kidney Dis. 2012 Sep;60(3):380-9.)上的一项研究评估了地中海饮食(MedDiet)对肾脏功能的影响,数据来自关于MedDiet饮食对原发性心血管疾病的干预效果的PREDIMED研究,该研究来自多中心的3个随机临床研究,采取横断面评估和1年的干预措施。参加的社区居民中男性年龄55-80岁、女性60-80岁,属于心血管疾病高危人群,这些人群来自西班牙的Reus。
 
  参与者被随机给于三种组合的饮食:MedDiet+初榨橄榄油;MedDiet+混合坚果;对照组的低脂饮食。对这些参与者进行eGFR的计算和尿白蛋白/肌酐的比值(ACR)测定。分析结果显示:一共785名参与者(55%为女性,平均年龄为67岁)起初的基础肾功能各组之间是相似的,在1年对665名居民饮食干预后,三种饮食组与肾功能改善相关,eGFR分别增加了4.7、3.5和4.1,均与基础值存在显著差异,而组间增加的eGFR未见显著差异;在矫正共同因素后,参与者干预后其ACR却未见改变。
 
  这些研究结果提示了MedDiet饮食并不能改善处于心血管疾病高危老年人群的肾功能,与低脂饮食收益是相似的。

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    2013-06-30 yese
  2. [GetPortalCommentsPageByObjectIdResponse(id=1850526, encodeId=81fb185052673, content=<a href='/topic/show?id=46c682469e4' target=_blank style='color:#2F92EE;'>#肾功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82469, encryptionId=46c682469e4, topicName=肾功能)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28d456, createdName=yese, createdTime=Sun Jun 30 03:25:00 CST 2013, time=2013-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497764, encodeId=a219149e7643b, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Sep 06 01:25:00 CST 2012, time=2012-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575412, encodeId=f4fe15e5412fd, content=<a href='/topic/show?id=cd9941326bc' target=_blank style='color:#2F92EE;'>#地中海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41326, encryptionId=cd9941326bc, topicName=地中海)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=303116130321, createdName=wgx311, createdTime=Thu Sep 06 01:25:00 CST 2012, time=2012-09-06, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1850526, encodeId=81fb185052673, content=<a href='/topic/show?id=46c682469e4' target=_blank style='color:#2F92EE;'>#肾功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82469, encryptionId=46c682469e4, topicName=肾功能)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28d456, createdName=yese, createdTime=Sun Jun 30 03:25:00 CST 2013, time=2013-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497764, encodeId=a219149e7643b, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Sep 06 01:25:00 CST 2012, time=2012-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575412, encodeId=f4fe15e5412fd, content=<a href='/topic/show?id=cd9941326bc' target=_blank style='color:#2F92EE;'>#地中海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41326, encryptionId=cd9941326bc, topicName=地中海)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=303116130321, createdName=wgx311, createdTime=Thu Sep 06 01:25:00 CST 2012, time=2012-09-06, status=1, ipAttribution=)]
    2012-09-06 wgx311
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