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AM HEART J:流感疫苗可降低心血管疾病风险!

2017-11-16 MedSci MedSci原创

本研究的目的旨在评估流感疫苗在老年人中预防主要心血管不良事件(MACEs)的作用,尤其在流感样疾病患者中。本次回顾性对照研究纳入了2000-2013年台湾健康保险研究数据库中年龄大于65岁的老年人,并对每一个MACE事件根据患者的年龄、入组时间和MACE危险因素选择配对对照。分析结果显示,接种过流感疫苗的老年人整体MACE发生风险更低(OR  0.80, 95% CI 0.78-0.82

本研究的目的旨在评估流感疫苗在老年人中预防主要心血管不良事件(MACEs)的作用,尤其在流感样疾病患者中。

本次回顾性对照研究纳入了2000-2013年台湾健康保险研究数据库中年龄大于65岁的老年人,并对每一个MACE事件根据患者的年龄、入组时间和MACE危险因素选择配对对照。分析结果显示,接种过流感疫苗的老年人整体MACE发生风险更低(OR  0.80, 95% CI 0.78-0.82, P < 0.001),心梗发生率更低(OR 0.80, 95% CI 0.76-0.84, P <0 .001),缺血性卒中发生率也更低(OR 0.80, 95% CI 0.77-0.82, P <0 .001)。有流感样疾病史的老年人的MACE发生风险更高(OR 1.24, 95% CI 1.18-1.29, P <0 .001),心梗发生风险更高(OR 1.46, 95% CI 1.34-1.59, P <0 .001),缺血性卒中发生风险也更高(OR 1.16, 95% CI 1.10-1.22, P < 0.001)。此外,流感疫苗的接种可以降低流感样疾病带来的心血管不良风险。

研究结果显示,接种过流感疫苗的老年人整体心血管不良事件发生风险更低,有流感样疾病史的老年人心血管不良事件发生风险更高。

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    2017-11-18 zhaojie88
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    2017-11-18 slcumt

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