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NEJM:危重病人气管插管时袋式面罩通气效果分析

2019-02-28 xing.T 网络

由此可见,在接受气管插管的重症患者中,接受袋式通气的患者的氧饱和度较高,严重低氧血症的发生率低于未接受通气的患者。

低氧血症是危重病人气管插管时最常见的并发症,可能会增加心脏骤停和死亡的风险。在重症患者的气管插管期间使用袋式面罩装置(袋式面罩通气)进行正压通气是否可以预防低氧血症而不增加误吸风险仍然存在争议。

近日,顶级医学期刊NEJM上发表了一篇研究文章,在美国七个重症监护室进行的多中心随机试验中,研究人员随机分配将需要气管插管的成人在诱导和喉镜检查之间接受袋式面罩装置通气或无袋式面罩通气。该研究的主要结局是在诱导间隔和气管插管后2分钟期间观察到的最低氧饱和度。次要结局是严重低氧血症的发生率,定义为氧饱和度低于80%。

在纳入的401名患者中,袋式通气组的最低血氧饱和度中位数为96%(四分位数间距为87-99),无通气组为93%(四分位数范围为81-99)(P=0.01)。袋式通气组共21例患者(10.9%)出现严重低氧血症,而无通气组有45例患者(22.8%)(相对危险度为0.48; 95%置信区间[CI]为0.30-0.77)。在袋式通气组2.5%的患者和无通气组4.0%的患者在插管期间发生了操作员报告的抽吸(P=0.41)。气管插管后48小时胸部X线片新发不透明影分别为16.4%和14.8%(P=0.73)。

由此可见,在接受气管插管的重症患者中,接受袋式通气的患者的氧饱和度较高,严重低氧血症的发生率低于未接受通气的患者。

原始出处:

Jonathan D. Casey,et al.Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults.NEJM.2019.https://www.nejm.org/doi/full/10.1056/NEJMoa1812405

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    2019-03-04 龙胆草

    学习谢谢分享

    0

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    2019-02-28 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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