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Thorax:非小细胞肺癌患者年龄、贫困和特定合并症与接受大手术的关联

2018-08-15 xiangting MedSci原创

合并症在患者是否接受手术方面发挥着重要作用,但不能完全解释在早期患者中观察到的社会经济差距。

这项研究调查了社会经济差距和主要预后因素在英国肺癌患者接受大手术治疗中的作用。

这项研究包括2012年英国诊断为非小细胞肺癌的31351名患者。全国人口癌症登记的数据与医院事件统计和全国肺癌审计数据联网,以获取有关癌症分期、表现状态和合并症信息,并确定接受大手术治疗的患者。为了描述预后因素与手术之间的关联,研究人员进行了两种不同的分析:一种使用多因素logistic回归,一种估算死亡和手术的病因特异性危险。这两种分析使用多重填补处理缺失数据。

有充分的证据表明合并症"充血性心力衰竭"、"脑血管病"和"慢性阻塞性肺病"减少了早期患者接受手术的机会。还观察到接受手术时的性别差异和显著年龄差异。尽管调整了性别、诊断年龄、合并症、诊断时分期、表现状态和PET-CT扫描适应症,但两种分析中仍存在社会经济差距:更多的贫困人口肺癌早期接受手术的几率更低。

合并症在患者是否接受手术方面发挥着重要作用,但不能完全解释在早期患者中观察到的社会经济差距。未来针对专科医院就诊和距离、以及患者对接受手术认知和选择的调查,有助于解决这些持续的社会经济不平等。

原始出处:

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    2018-08-16 liumin1987

    非小细胞肺癌的研究。

    0

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Baidu
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Baidu
map
Baidu
map