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J Intern Med:鱼吃的太多或太少,都会增加死亡风险?

2016-09-27 Moon 译 MedSci原创

摄入鱼和全因死亡率究竟有什么关系?目前的流行病学研究提供了不一致的结果。我们对一个大型的以人群为基础的瑞典男性和女性进行了研究,探究鱼摄入量和全因死亡率之间的剂量反应关系。 这项研究包括了72 522名参与者(33 973名女性和38 549名男性),年龄在45岁至83岁之间,来自瑞典乳腺钼靶摄影队列和瑞典男性队列。在1997年,通过自填式问卷调查,获得了参与者鱼摄入量等相关信息。对参与者随

摄入鱼和全因死亡率究竟有什么关系?目前的流行病学研究提供了不一致的结果。我们对一个大型的以人群为基础的瑞典男性和女性进行了研究,探究鱼摄入量和全因死亡率之间的剂量反应关系。

这项研究包括了72 522名参与者(33 973名女性和38 549名男性),年龄在45岁至83岁之间,来自瑞典乳腺钼靶摄影队列和瑞典男性队列。在1997年,通过自填式问卷调查,获得了参与者鱼摄入量等相关信息。对参与者随访了17年(从1998年1月1日至2014年12月31日),从瑞典死亡登记册识别死亡和死因相关数据。使用Cox比例风险回归模型,评估鱼摄入量和全因死亡率之间的联系。

在随访过程中,发生了16 730例死亡(7168名女性和9562名男性)。鱼摄入量和全因死亡率之间的剂量反应关系呈U形。与鱼摄入量居中的参与者相比,更低水平的鱼摄入量与更高的全因死亡风险相关,尤其是不吃鱼的参与者,风险最高:女性,风险高出25%(HR 1.25; 95% CI 1.11, 1.40);男性,风险高出19%(HR 1.19; 95% CI: 1.07, 1.32)。与鱼摄入量居中的参与者相比,更高水平的鱼摄入量与更高的全因死亡风险相关,仅限于女性;摄入量最高(每天80克)的女性,风险高出39%(HR 1.39; 95% CI: 1.15, 1.68)。

结果表明,鱼摄入量和全因死亡率之间的剂量反应关系呈U形,尤其是对于女性。

原始出处:

A. Bellavia,et al.Fish consumption and all-cause mortality in a cohort of Swedish men and women.J Intern Med.7 SEP 2016

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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    2016-10-24 ylzr123

    鱼摄入量和全因死亡率之间的剂量反应关系呈U形,尤其是对于女性。这个结果让我们很吃惊。

    0

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    2016-10-01 doctorJiangchao

    继续学习

    0

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authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Sep 28 15:55:40 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137009, encodeId=693813e00985, content=人体讲究平衡,什么都是过犹不及, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Wed Sep 28 14:03:51 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=136774, encodeId=3bfb136e743e, content=新概念!学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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    2016-09-29 xmax889

    不错,我就属于中间型的

    0

  6. 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    2016-09-28 刘煜

    学习了谢谢。

    0

  7. 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    2016-09-28 刘煜

    学习了谢谢。

    0

  8. 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authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Sep 28 15:55:40 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137009, encodeId=693813e00985, content=人体讲究平衡,什么都是过犹不及, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Wed Sep 28 14:03:51 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=136774, encodeId=3bfb136e743e, content=新概念!学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55a51936147, createdName=goddess 328, createdTime=Wed Sep 28 01:41:40 CST 2016, time=2016-09-28, status=1, ipAttribution=)]
    2016-09-28 刘煜

    学习了谢谢。

    0

  9. 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authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Sep 28 15:55:40 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137009, encodeId=693813e00985, content=人体讲究平衡,什么都是过犹不及, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Wed Sep 28 14:03:51 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=136774, encodeId=3bfb136e743e, content=新概念!学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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    2016-09-28 舒心和人

    人体讲究平衡,什么都是过犹不及

    0

  10. 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authenticateStatus=null, createdAvatar=, createdBy=55a51936147, createdName=goddess 328, createdTime=Wed Sep 28 01:41:40 CST 2016, time=2016-09-28, status=1, ipAttribution=)]
    2016-09-28 goddess 328

    新概念!学习!

    0

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