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Cell Metab: 精加工食品导致暴饮暴食和体重增加

2019-05-27 佚名 生物通

营养专家长期以来一直怀疑,过去50年来精加工食品的消耗增加是导致肥胖流行的主要原因。但是因为饮食习惯研究很复杂,难以直接关联。

营养专家长期以来一直怀疑,过去50年来精加工食品的消耗增加是导致肥胖流行的主要原因。但是因为饮食习惯研究很复杂,难以直接关联。



5月16日Cell Metabolism杂志上发表的一项最新研究中,研究人员报告了第一项随机对照试验的结果,该试验直接比较了精加工和未加工饮食之间卡路里消耗和体重增加的差异。研究小组发现,即使两种饮食的碳水化合物,脂肪,糖,盐和卡路里含量一致,精加工饮食也会导致摄入更多的食物,增加体重。

“我对这项研究的结果感到惊讶,因为我认为如果我们将这两种饮食的成分,如糖,脂肪,碳水化合物,蛋白质和钠等统一一致,那么精加工食品不会有任何神奇之处,”文章通讯作者,糖尿病消化与肾病研究所NIHKevin Hall说,“但我们发现,事实上,精加工饮食会让人摄取更多的卡路里,导致体重和体脂增加。”

这项研究招募了20名健康志愿者,他们在NIH临床研究部门参与一个月。每个参与者都摄入了精加工饮食或未加工的饮食两周,然后调转。参与者每天获得三餐,并且可以全天饮用瓶装水和食用精加工或未加工的零食。研究人员告诉他们可以吃到想要的东西,然后测量他们消耗的数量。

研究人员使用NOVA食品分类系统,根据加工的程度和目的对食品进行分类,例如,一种精加工早餐包括Honey Nut Cheerios(添加纤维的全脂牛奶),包装蓝莓松饼和人造黄油;未加工的是用普通希腊酸奶,草莓,香蕉,核桃,盐和橄榄油制成的冻糕,以及鲜榨柠檬汁苹果片。参与者称,这两种食物都很好吃,令人满意,不存在食物偏好。

参与者食用精加工食品的时间里,与食用未加工食品的时间相比,平均每天摄入的热量多出508卡路里。精加工饮食两周导致平均体重增加2磅,而未加工饮食的两周平均体重减轻2磅。

代谢测试显示,当参与者吃精加工食物时,他们消耗的能量比他们吃未经加工的饮食时消耗的能量更多,但不能抵消他们卡路里增加的数量。由于参与者健康且测试期仅持续一个月,因此研究人员未发现其他健康指标(如肝脏脂肪或血糖)存在显着差异。

研究人员提出了几个假设,说明为什么精加工饮食的人会摄入更多的食物。

当人们吃精加工饮食时,他们的吃得更快。“食物的质地或感官特性可能会让它们吃得更快。如果你吃得很快,也许无法给你的肠道足够的时间向你的大脑发出你已经饱了的信号。当这种情况发生时,你可能会很容易吃得过饱。”

另一个假设是固体食物与饮料的不同。为了平衡膳食纤维,匹配整体饮食的卡路里密度,将饮料到添加到精加工食物中,例如果汁和柠檬水(带来纤维)。但是一些研究人员认为饮料对饱腹感的贡献与固体食物一样。因此,精加工饮食中固体食物的较高卡路里密度可能导致人们增加其总卡路里的摄入量。

第三个因素可能是尽管饮食尽可能地匹配,但未加工的饮食含有略多的蛋白质,约15.6%,而精加工的饮食则为14%。“可能是人们为了达到某些蛋白质目标,吃得更多。”

未来的研究将试图解释这些因素,并探讨增加卡路里消耗背后的可能机制。

不过研究人员也提出了该研究的一个重要局限性:因为所有食物都是为参与者准备好的,所以没有考虑到他们制作的方便程度或费用。

Hall说:“我们知道有很多因素会导致人们为什么选择精加工餐而不是未经加工的餐。特别是对于社会经济水平较低的人们,我们需要注意创造未加工食品所需的技能,设备,知识和费用。”

原始出处:Kevin D. Hall, Alexis Ayuketah, Robert Brychta, et al. Ultra-processed diets cause excess calorie intake and weight gain: A one-month inpatient randomized controlled trial of ad libitum food intake. Cell Metab. May 16, 2019

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    2019-06-09 一闲
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    2019-07-28 guojianrong
  5. [GetPortalCommentsPageByObjectIdResponse(id=2046571, encodeId=a5a420465e1fc, content=<a href='/topic/show?id=22a8e640990' target=_blank style='color:#2F92EE;'>#精加工#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76409, encryptionId=22a8e640990, topicName=精加工)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f98e185, createdName=psybestwish, createdTime=Sun Jul 28 04:33:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896499, encodeId=a1e3189649906, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Jun 09 00:33:00 CST 2019, time=2019-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871298, encodeId=275118e1298af, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Mon Aug 05 23:33:00 CST 2019, time=2019-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888019, encodeId=e5ba1888019ad, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Jul 28 03:33:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1961581, encodeId=100f196158124, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Wed Aug 14 22:33:00 CST 2019, time=2019-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298235, encodeId=a7081298235ee, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Wed May 29 05:33:00 CST 2019, time=2019-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417428, encodeId=c998141e42887, content=<a href='/topic/show?id=29ad60210f3' target=_blank style='color:#2F92EE;'>#暴饮暴食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60210, encryptionId=29ad60210f3, topicName=暴饮暴食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09a33274256, createdName=redcrab, createdTime=Wed May 29 05:33:00 CST 2019, time=2019-05-29, status=1, ipAttribution=)]
    2019-08-14 维他命
  6. [GetPortalCommentsPageByObjectIdResponse(id=2046571, encodeId=a5a420465e1fc, content=<a href='/topic/show?id=22a8e640990' target=_blank style='color:#2F92EE;'>#精加工#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76409, encryptionId=22a8e640990, topicName=精加工)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f98e185, createdName=psybestwish, createdTime=Sun Jul 28 04:33:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896499, encodeId=a1e3189649906, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Jun 09 00:33:00 CST 2019, time=2019-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871298, encodeId=275118e1298af, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Mon Aug 05 23:33:00 CST 2019, time=2019-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888019, encodeId=e5ba1888019ad, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Jul 28 03:33:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1961581, encodeId=100f196158124, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Wed Aug 14 22:33:00 CST 2019, time=2019-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298235, encodeId=a7081298235ee, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Wed May 29 05:33:00 CST 2019, time=2019-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417428, encodeId=c998141e42887, content=<a href='/topic/show?id=29ad60210f3' target=_blank style='color:#2F92EE;'>#暴饮暴食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60210, encryptionId=29ad60210f3, topicName=暴饮暴食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09a33274256, createdName=redcrab, createdTime=Wed May 29 05:33:00 CST 2019, time=2019-05-29, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=2046571, encodeId=a5a420465e1fc, content=<a href='/topic/show?id=22a8e640990' target=_blank style='color:#2F92EE;'>#精加工#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76409, encryptionId=22a8e640990, topicName=精加工)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f98e185, createdName=psybestwish, createdTime=Sun Jul 28 04:33:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896499, encodeId=a1e3189649906, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Jun 09 00:33:00 CST 2019, time=2019-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871298, encodeId=275118e1298af, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Mon Aug 05 23:33:00 CST 2019, time=2019-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888019, encodeId=e5ba1888019ad, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Jul 28 03:33:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1961581, encodeId=100f196158124, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Wed Aug 14 22:33:00 CST 2019, time=2019-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298235, encodeId=a7081298235ee, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Wed May 29 05:33:00 CST 2019, time=2019-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417428, encodeId=c998141e42887, content=<a href='/topic/show?id=29ad60210f3' target=_blank style='color:#2F92EE;'>#暴饮暴食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60210, encryptionId=29ad60210f3, topicName=暴饮暴食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09a33274256, createdName=redcrab, createdTime=Wed May 29 05:33:00 CST 2019, time=2019-05-29, status=1, ipAttribution=)]
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