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J Endod:药物性下颌骨坏死引发的牙髓疾病:一例病例汇报

2020-06-07 lishiting MedSci原创

虽然双磷酸盐(BPs)被广泛应用于治疗骨质疏松症,但是它可能会导致下颌骨坏死。这篇病例汇报描述的是一例没有牙齿拔除或手术治疗史的患者罹患药物性下颌骨坏死(MRONJ)伴随次级牙髓疾病的病例。

虽然双磷酸盐(BPs)被广泛应用于治疗骨质疏松症,但是它可能会导致下颌骨坏死。这篇病例汇报描述的是一例没有牙齿拔除或手术治疗史的患者罹患药物性下颌骨坏死(MRONJ)伴随次级牙髓疾病的病例。

一名79岁的女性患者,切牙区域牙龈有脓性渗出物。患者使用BPs 9年。#6牙齿在普通诊所实施了根管治疗。除了#6牙齿,其余所有牙牙髓电活力测试显示牙髓有活力。CT影像显示有骨坏死的体征,诊断为MRONJ。#7和#8牙齿最初牙髓显示有活力,随后对热刺激和牙髓电活力测试反应呈阴性。对#6-8牙齿进行根管治疗并检测其状态。第一次就诊后9个月的CT影像显示,骨缺损扩大,伴随坏死骨分离,随后在口颌面外科实施了坏死骨切除和刮治术。

牙齿最初就诊时表现出活髓而后发展为牙髓无活力,表明#6-8牙齿发展为牙髓致病状态是MRONJ的结果。

原始出处

Kazuki Kiho, Shinichiro Sumitomo, et al. Pulpal Disease Arising From Medication-Related Osteonecrosis of the Jaw: A Case Report. J Endod., 2020 May 8;S0099-2399(20)30301-0. doi: 10.1016/j.joen.2020.04.010.

 

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    2021-02-25 zll0634
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    2021-05-23 jxrzshh
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    2020-10-13 xlysu
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  5. 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  6. 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createdAvatar=null, createdBy=6e2f14815893, createdName=zhmscau, createdTime=Tue Jun 09 14:01:12 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
    2020-06-09 millore
  7. 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createdAvatar=null, createdBy=6e2f14815893, createdName=zhmscau, createdTime=Tue Jun 09 14:01:12 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
    2020-06-09 珙桐
  8. 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