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Gastric Cancer:不同分期胃癌根治术后的最适随访时间!

2021-01-07 MedSci原创 MedSci原创

外科医生常常会面临一个很重要的问题,即如何制定胃癌根治性手术后的随访计划。目前,胃癌根治性手术后通常随访5年。不过,到底应该随访多久仍存在争议。

外科医生常常会面临一个很重要的问题,即如何制定胃癌根治性手术后的随访计划。目前,胃癌根治性手术后通常随访5年。不过,到底应该随访多久仍存在争议。

本研究回顾性分析了1975年-2010年在多伦多医院接受根治性胃切除术的患者的临床病理数据库,分析了术后各阶段的随访率和复发率,并确定了术后复发率低于1%时的随访终点。

随访率随时间的变化

共纳入了5235名符合条件的患者。5年的随访率为90.3%。随着随访时间的延长,随访率明显降低:10年 52.7%、15年 38.3%、20年 10.3%。共有850例(16.2%)患者被确认复发,其中50例患者是5年后复发的。

不同分期患者术后存活预后

根据分期(<1%复发风险)明确的合适的随访终点分别为:IA期 2年、IB期 4年、IIA期 6年、IIB期 9年、IIIA期 7年、IV期(治愈) 8年。对于IIIB期和IIIC期胃癌患者,也存在复发风险。

总之,不同分期的胃癌在切除后的适宜随访监测时间可能不同。虽然I期胃癌的随访时间可以缩短到5年以下,但晚期胃癌(如III期或IV期疾病)术后5年后仍存在复发风险,因此需要进行延长随访。该研究结果可能有助于外科医生制定胃癌患者的术后随访计划。

原始出处:

Yago, A., Haruta, S., Ueno, M. et al. Adequate period of surveillance in each stage for curatively resected gastric cancer: analyzing the time and rates of recurrence. Gastric Cancer (2021). https://doi.org/10.1007/s10120-020-01147-4

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    2021-10-11 许安
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    2021-05-03 skhzy
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topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Sat Jan 09 03:08:08 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914417, encodeId=56cd91441e29, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f48a5450863, createdName=ms4000001855355063, createdTime=Thu Jan 07 15:29:37 CST 2021, time=2021-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914392, encodeId=d2cf914392ca, content=<a href='/topic/show?id=f9e2832202f' target=_blank style='color:#2F92EE;'>#胃癌#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83220, encryptionId=f9e2832202f, 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  5. 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topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Sat Jan 09 03:08:08 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914417, encodeId=56cd91441e29, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f48a5450863, createdName=ms4000001855355063, createdTime=Thu Jan 07 15:29:37 CST 2021, time=2021-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914392, encodeId=d2cf914392ca, content=<a href='/topic/show?id=f9e2832202f' target=_blank style='color:#2F92EE;'>#胃癌#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83220, encryptionId=f9e2832202f, topicName=胃癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Jan 07 15:08:20 CST 2021, time=2021-01-07, status=1, ipAttribution=)]
    2021-03-26 ms5000000357833599

    学到了

    0

  6. 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createdTime=Sun Jan 10 23:46:50 CST 2021, time=2021-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399747, encodeId=7c171399e474a, content=<a href='/topic/show?id=72406223398' target=_blank style='color:#2F92EE;'>#根治术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62233, encryptionId=72406223398, topicName=根治术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03a52234941, createdName=bluefate122, createdTime=Sat Jan 09 03:08:08 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586202, encodeId=875e15862029b, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, 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topicName=胃癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Jan 07 15:08:20 CST 2021, time=2021-01-07, status=1, ipAttribution=)]
    2021-01-10 ms1000000591710906

    学习了

    0

  7. 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  8. 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topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Sat Jan 09 03:08:08 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914417, encodeId=56cd91441e29, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f48a5450863, createdName=ms4000001855355063, createdTime=Thu Jan 07 15:29:37 CST 2021, time=2021-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914392, encodeId=d2cf914392ca, content=<a href='/topic/show?id=f9e2832202f' target=_blank style='color:#2F92EE;'>#胃癌#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83220, encryptionId=f9e2832202f, topicName=胃癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Jan 07 15:08:20 CST 2021, time=2021-01-07, status=1, ipAttribution=)]
    2021-01-09 jeanqiuqiu
  9. 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    2021-01-07 ms4000001855355063

    学习到了

    0

  10. 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topicName=胃癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Jan 07 15:08:20 CST 2021, time=2021-01-07, status=1, ipAttribution=)]
    2021-01-07 zhouqu_8

    #胃癌#学习了

    0

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