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Brit J Cancer:体重正常人群体重增加可降低食道癌风险

2017-09-29 zhangfan MedSci原创

对于体重正常人群,体重指数增加可降低食管鳞状细胞癌风险

近日研究人员考察了体重指数(BMI)变化对成人食管鳞状细胞癌(ESCC)风险的影响。

研究依据日本公共健康前瞻性研究数据,在1990-94年间共招募了103238名参与者。参与者基线平均年龄20岁,在基线、5或和10年进行问卷随访。研究人员通过Cox比例风险回归模型考察BMI变化与EDCC风险之间的关系。

研究期间,共新发342例ESCC病例。体重增加与ESCC风险增高存在相关性,5年体重指数每增加1%,可降低15%的食管鳞状细胞癌风险 (95% CI 9-21%)。时变模型结果验证了上述结果。BMI变化的影响不随性别、吸烟或饮酒状态而改变,但仅限于评定为非超重人群。

研究认为,对于体重正常人群,体重指数增加可降低食管鳞状细胞癌风险。

始出处:


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    2018-02-17 xjy13
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    2017-12-03 sjq027
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    2017-10-17 yunger

    很好看.学习了

    0

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    2017-09-30 戒馋,懒,贪

    谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1716965, encodeId=86371e169651b, content=<a href='/topic/show?id=f8a98002eb1' target=_blank style='color:#2F92EE;'>#群体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80027, encryptionId=f8a98002eb1, topicName=群体)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6c0832353243, createdName=xjy13, createdTime=Sat Feb 17 07:32:00 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061676, encodeId=99c820616e6c7, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun Dec 03 14:32:00 CST 2017, time=2017-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=253595, encodeId=3bf825359588, content=很好看.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/mzZkwf53jx0oribz8WkmVTPTSib4iaRMXz6nkEOaqWPjgyYWQoLa8J2WCicWvb8SrhhZz5sgUcwmQnMQ1lJcA7Fhxg/0, createdBy=9b182084756, createdName=yunger, createdTime=Tue Oct 17 06:47:34 CST 2017, time=2017-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298219, encodeId=5b9a12982198d, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Oct 01 00:32:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=249047, encodeId=addb24904e70, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Sep 30 08:08:00 CST 2017, time=2017-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248783, encodeId=e7cf248e832c, content=好好努力学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 29 11:39:50 CST 2017, time=2017-09-29, status=1, ipAttribution=)]
    2017-09-29 忠诚向上

    好好努力学习

    0

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