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AAOS:髋部骨折术后入住ICU升压药支持生存率较差

2014-03-27 佚名 DXY

髋部骨折病例伴有明显的合并症发生率及死亡率。但到目前为止,尚缺乏对因为出现并发症而入住ICU监护治疗的髋部骨折病例的相关研究。本研究试图确定入住ICU的危险因素,以及与ICU监护相关的疗效。 该试验回顾性分析了来自于单一医院2002年至2012年之间治疗的1279例髋部骨折的连续病例。患者平均年龄为83岁(范围:67-92岁)。比较入住ICU病例与未入住病例的人口统计

髋部骨折病例伴有明显的合并症发生率及死亡率。但到目前为止,尚缺乏对因为出现并发症而入住ICU监护治疗的髋部骨折病例的相关研究。本研究试图确定入住ICU的危险因素,以及与ICU监护相关的疗效。

该试验回顾性分析了来自于单一医院2002年至2012年之间治疗的1279例髋部骨折的连续病例。患者平均年龄为83岁(范围:67-92岁)。比较入住ICU病例与未入住病例的人口统计学参数、围手术期并发症以及住院期间死亡率之间的差异。重点关注ICU监护治疗期间升压药的使用情况。

试验中总共有470例患者术后需要入住ICU监护治疗,占所有髋部骨折病例的36.7%.ICU治疗组中45例(9.4%)患者因顽固性低血压予以升压药治疗。约93%的接受升压药治疗的病例在末次随访之前死亡。术后30天、90天和1年的死亡率分别为36%、49%和60%.入住ICU但无需升压药治疗的病例末次随访时的死亡率为68%,其中术后30天的死亡率为9.6%.术后未入住ICU的病例在末次随访时的死亡率为46.6%.接受升压药和未接受升压药的病例在年龄、性别、美国麻醉医师协会(ASA)分级、骨折治疗方式、医师类别以及手术时间之间均无显著差异。接受升压药治疗病例的住院时间显著长于未接受者(p<0.00001)。

髋部骨折术后需要入住ICU监护治疗预示着生存率较差。本组总共有36.7%的髋部骨折病例需要入住ICU,而其中接受升压药治疗病例在末次随访时的死亡率高达93%.术前采用一定的措施使这一类病情严重的患者身体状况达到最佳状态再接受手术治疗极为重要。

原始出处:

Diren Arsoy, Atul F. Kamath, Joseph R. Cass, Arun Subramanian,Stephen A. Sems, Robert T. Trousdale.ICU Admission and Vasopressor Support Results in Poor Survivorship after Hip Fracture Surgery.AAOS Mar 12, 2014

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    2014-08-16 yinhl1978
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    2014-03-29 liuquan

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