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Omega-3脂肪酸或可降低HIV患者心血管疾病的发病风险

2016-10-31 MedSci MedSci原创

据IDWeek 2016上一项新的研究展示表明,与安慰剂相比,接受抗逆转录病毒治疗稳定的HIV患者每日摄入较高水平的Omega-3脂肪酸可显著降低甘油三酯和C-反应蛋白的水平。HIV患者是心血管疾病的高危患者,该研究中,研究人员进行了一项随机对照试验以探究高剂量的ω-3脂肪酸在HIV患者中对血脂、炎症和血管功能的长期作用。研究共纳入了117名HIV感染者,均接受抗逆转录病毒治疗。随机分配分别每天接

据IDWeek 2016上一项新的研究展示表明,与安慰剂相比,接受抗逆转录病毒治疗稳定的HIV患者每日摄入较高水平的Omega-3脂肪酸可显著降低甘油三酯和C-反应蛋白的水平。

HIV患者是心血管疾病的高危患者,该研究中,研究人员进行了一项随机对照试验以探究高剂量的ω-3脂肪酸在HIV患者中对血脂、炎症和血管功能的长期作用。

研究共纳入了117名HIV感染者,均接受抗逆转录病毒治疗。随机分配分别每天接受4克纯化的ω-3脂肪酸(n = 61)或安慰剂(n = 56)。患者的平均年龄为51岁,21%的患者为女性,95%的患者病毒抑制。

结果,24个月后,治疗组患者的甘油三酯下降至68毫克/分升,安慰剂组下降22毫克/分升。治疗组C反应蛋白降低0.3 mg / L,安慰剂组升高0.6 mg(P =0.008)。

高密度脂蛋白胆固醇或肱动脉反应性上两组之间并无显著差异,在严重不良反应事件上两组并无差别。

而结果显示,长期补充ω-3脂肪酸可降低甘油三酯的水平,也可减缓HIV阳性患者的慢性炎症。研究人员表示仍需一年以上治疗时间的研究以探究这种治疗是否可改善血管功能。

原始出处:

Gerard Gallagher.  Omega-3s decreased median triglycerides and CRP in HIV patients on ART. Healio, October 28, 2016.

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    2016-10-31 知难而进

    学习了g'n

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1778762, encodeId=0cd11e78762e9, content=<a href='/topic/show?id=2216130401' target=_blank style='color:#2F92EE;'>#3脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1304, encryptionId=2216130401, topicName=3脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Tue Apr 18 06:15:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779138, encodeId=b0811e79138fe, content=<a href='/topic/show?id=2216130401' target=_blank style='color:#2F92EE;'>#3脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1304, encryptionId=2216130401, topicName=3脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sat Nov 05 14:15:00 CST 2016, time=2016-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2003354, encodeId=b936200335450, content=<a href='/topic/show?id=5012890397' target=_blank style='color:#2F92EE;'>#HIV患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8903, encryptionId=5012890397, topicName=HIV患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b505306, createdName=医生2394, createdTime=Tue Sep 26 22:15:00 CST 2017, time=2017-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498080, encodeId=965d149808002, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Wed Nov 02 11:15:00 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152463, encodeId=d8c61524631d, content=学习了g'n, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Mon Oct 31 21:49:16 CST 2016, time=2016-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152450, encodeId=4d3615245008, content=感觉不是很明确, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160923/IMG57E54D670B3C08868.jpg, createdBy=e90b1956497, createdName=Carlos007, createdTime=Mon Oct 31 21:41:22 CST 2016, time=2016-10-31, status=1, ipAttribution=)]
    2016-10-31 Carlos007

    感觉不是很明确

    0

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