Circulation：动脉粥样硬化中的重要环节！

2017-02-02 MedSci MedSci原创

坏死的中心一直是脆弱的动脉粥样硬化斑块的标志。尽管凋亡细胞在几乎所有的其他组织床中可以被迅速清除，但是在病变血管中它们的去除似乎显着受损。最新的证据表明，这种现象是由胞葬作用（Efferocytosis）缺陷引起的，一种凋亡组织被吞噬细胞（如巨噬细胞）识别并吞噬的过程。遗传和实验数据表明，胞葬作用受损发生在动脉粥样硬化造成的所谓的“吃我配体”失调中，它可以调控决经历程序性细胞死亡的细胞吞噬。以下是

坏死的中心一直是脆弱的动脉粥样硬化斑块的标志。尽管凋亡细胞在几乎所有的其他组织床中可以被迅速清除，但是在病变血管中它们的去除似乎显着受损。

最新的证据表明，这种现象是由胞葬作用（Efferocytosis）缺陷引起的，一种凋亡组织被吞噬细胞（如巨噬细胞）识别并吞噬的过程。

遗传和实验数据表明，胞葬作用受损发生在动脉粥样硬化造成的所谓的“吃我配体”失调中，它可以调控决经历程序性细胞死亡的细胞吞噬。

以下是最近数据的总结，其指示胞葬作用是损伤扩大的主要不受欢迎的驱动因素，但是也可能作为防止斑块进展的潜在靶点的可逆性缺陷。

原始出处：
Kojima Y, Weissman IL, Leeper NJ. The Role of Efferocytosis in Atherosclerosis. Circulation. 2017 Jan 31;135(5):476-489.

本文系梅斯医学（MedSci）原创编译整理，转载需授权！

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言

评论区 (7)

#插入话题

插入图片

[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-04-08 fzwish20000

#重要环节#

70 0
[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-03-05 huangshifeng

#粥样硬化#

115 0
[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-02-04 liujianhua1955

很受益

82 0
[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-02-03 jihuaijun1112

学习。。。。。

109 0
[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-02-03 Healer

嗯，学习了新的内容

106 0
[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-02-03 卡圣

长见识了

76 0
[GetPortalCommentsPageByObjectIdResponse(id=1814860, encodeId=9d22181486003, content=<a href='/topic/show?id=3a18960e024' target=_blank style='color:#2F92EE;'>#重要环节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96070, encryptionId=3a18960e024, topicName=重要环节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Sat Apr 08 11:54:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944432, encodeId=71c8194443229, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Sun Mar 05 23:54:00 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174144, encodeId=95901e41448b, content=很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=475d1368230, createdName=liujianhua1955, createdTime=Sat Feb 04 12:54:24 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173911, encodeId=4bbd1e391174, content=学习。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Feb 03 08:17:56 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173883, encodeId=d9cb1e3883bb, content=嗯，学习了新的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170129/IMG588DDC7F8AC3C1672.jpg, createdBy=e4971654967, createdName=Healer, createdTime=Fri Feb 03 05:54:35 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173878, encodeId=b6b31e3878cf, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Fri Feb 03 05:09:06 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173853, encodeId=739e1e38530c, content=稳定斑块，避免斑块脱落, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Feb 02 23:30:31 CST 2017, time=2017-02-02, status=1, ipAttribution=)]
2017-02-02 有备才能无患

稳定斑块，避免斑块脱落

113 0

内科

外科

专科科室

热点

按科室浏览

临床工具

科研工具

其他工具

科研数智化

真实世界研究解决方案

数字化学术传播解决方案

其它

心血管

Circulation：动脉粥样硬化中的重要环节！

相关资讯

科室

工具

服务