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Diabetologia:饮食干预限制妊娠期体重增加对妊娠期糖尿病患者胎儿生长的影响

2018-11-30 MedSci MedSci原创

本研究的目的是调查饮食治疗期间孕妇妊娠期体重增加(GWG)对妊娠期糖尿病(GDM)妊娠期胎儿生长的影响。 这是一项回顾性队列研究,调查显示,在2011年至2017年间,在丹麦哥本哈根Rigshospitalet糖尿病孕妇中心,共有382名女性在妊娠34周前连续诊断为GDM,且均为活单胞胎。研究人员将这些妇女分为三组,根据在饮食治疗期间(使用医学研究所指南)限制性(53%),适当(16%)和过

本研究的目的是调查饮食治疗期间孕妇妊娠期体重增加(GWG)对妊娠期糖尿病GDM)妊娠期胎儿生长的影响。

这是一项回顾性队列研究,调查显示,在2011年至2017年间,在丹麦哥本哈根Rigshospitalet糖尿病孕妇中心,共有382名女性在妊娠34周前连续诊断GDM,且均为活单胞胎。研究人员将这些妇女分为三组,根据在饮食治疗期间(使用医学研究所指南)限制性(53%),适当(16%)和过量(31%)每周GWG评估对能量限制性糖尿病饮食的依从性(6000 kJ  kJ/day [1434 kcal/day],大约50%的能量摄入来自碳水化合物,碳水化合物摄入量为175 g/day)。根据当地临床指南,必要时开始胰岛素治疗。

结果显示,葡萄糖耐量,HbA 1c,饮食治疗前每周GWGGDM诊断时体重与孕前体重之间的差异除以周数)和胎儿腹围SD评分276  ±5 1  周诊断GDM时(妊娠时间被给定为周)均可进行比较。随访10 0  ±5 1  周,其中54%接受补充胰岛素治疗,饮食治疗期间平均GWG分别为0 kg3 kg5 kg。饮食治疗过程中每周GWG过多,反映出饮食依从性差与从诊断GDM到妊娠晚期和婴儿出生体重-SD评分0.59±1.6HbA 1c增加有关(p  = 0.014)。相反,饮食治疗期间每周限制GWG,反映严格的饮食依从性与从诊断GDM到妊娠晚期和出生体重-SD评分为0.15±1.1的婴儿的HbA 1c降低(p = 0.001)相关,而胎龄较小的婴儿患病率未增加。在对混杂因素进行校正后,饮食治疗期间过量的GWG和晚期妊娠HbA 1c被确定为婴儿出生体重-SD评分(两个变量p = 0.02)的潜在可修正的临床预测因子。

饮食治疗期间限制GWG与患有GDM的女性中胎儿更健康的生长相关。确定饮食治疗期间的GWG和晚期妊娠HbA 1c为婴儿出生体重-SD评分的潜在可修正的临床预测因子。

原始出处:

Lise L. Kurtzhals, Sidse K. Nørgaard, The impact of restricted gestational weight gain by dietary intervention on fetal growth in women with gestational diabetes mellitus

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    2018-12-05 orangesking

    0

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GetPortalCommentsPageByObjectIdResponse(id=1251170, encodeId=e7d512511e095, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1253633, encodeId=c95d12536333d, content=<a href='/topic/show?id=9d5d44888a9' target=_blank style='color:#2F92EE;'>#妊娠期糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44888, encryptionId=9d5d44888a9, topicName=妊娠期糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298230, encodeId=998c129823060, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474655, encodeId=471f14e465514, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503584, encodeId=65d815035842e, content=<a href='/topic/show?id=c8a91012335b' target=_blank style='color:#2F92EE;'>#饮食干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101233, encryptionId=c8a91012335b, topicName=饮食干预)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0b369667354, createdName=pandamao2013, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042071, encodeId=0b3910420e165, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
    2018-12-02 orangesking

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1760912, encodeId=a4a31e6091219, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sun Sep 15 03:50:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638880, encodeId=4278163888013, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, 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GetPortalCommentsPageByObjectIdResponse(id=1251170, encodeId=e7d512511e095, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1253633, encodeId=c95d12536333d, content=<a href='/topic/show?id=9d5d44888a9' target=_blank style='color:#2F92EE;'>#妊娠期糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44888, encryptionId=9d5d44888a9, topicName=妊娠期糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298230, encodeId=998c129823060, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474655, encodeId=471f14e465514, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503584, encodeId=65d815035842e, content=<a href='/topic/show?id=c8a91012335b' target=_blank style='color:#2F92EE;'>#饮食干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101233, encryptionId=c8a91012335b, topicName=饮食干预)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0b369667354, createdName=pandamao2013, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042071, encodeId=0b3910420e165, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1760912, encodeId=a4a31e6091219, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sun Sep 15 03:50:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638880, encodeId=4278163888013, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdName=shenxlcyp, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298230, encodeId=998c129823060, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474655, encodeId=471f14e465514, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503584, encodeId=65d815035842e, content=<a href='/topic/show?id=c8a91012335b' target=_blank style='color:#2F92EE;'>#饮食干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101233, encryptionId=c8a91012335b, topicName=饮食干预)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0b369667354, createdName=pandamao2013, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042071, encodeId=0b3910420e165, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
  7. 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createdName=shenxlcyp, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298230, encodeId=998c129823060, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Dec 02 13:50:00 CST 2018, time=2018-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474655, encodeId=471f14e465514, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Dec 01 01:50:00 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
    2018-12-01 misszhang

    谢谢MedSci提供最新的资讯

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