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J INTERN MED：乳糖酶持续性和牛奶摄入量与髋部骨折和骨密度！

2018-03-15 xing.T MedSci原创

乳糖酶持续牛奶摄入量髋部骨折骨密度
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由此可见，丹麦人群的遗传性终生乳糖酶耐受的高牛奶摄入量与髋部骨折无关。荟萃分析还表明，乳糖酶持续性与骨折风险无关。基因乳糖酶持续性与股骨颈骨密度增高有关，而与腰椎或全髋关节BMD无关。

牛奶摄入量与骨折风险降低之间是否存在因果关系尚不明确。近日，内科学领域权威杂志Journal of Internal Medicine上发表一篇研究文章，研究人员旨在检验一个假设即基因决定的牛奶摄入量降低了骨折风险和增加骨密度（BMD）。

研究人员在三个丹麦前瞻性研究（n=97811，年龄≥20岁）中分析了牛奶摄入量、乳糖耐受性相关的LCT-13910 C/T（rs4988235）（TT和TC）与髋部骨折之间的相关性。我们从5个发表的欧洲北部人口研究加入了LCT-13910和骨折和骨密度的荟萃分析。

在丹麦的研究中，牛奶摄入量每周增加1杯发生髋部骨折校正后的风险比（HR）为1（95%可信区间为0.99-1.01）。每个等位基因牛奶摄入量为0.58（0.49-0.68）。在丹麦研究的荟萃分析中，随机效应中TT vs. CC发生任何骨折的比值比为0.86（0.61-1.21；I2=73%）和TC vs. CC为0.90（0.68-1.21；I2=63%）。TT vs. CC在股骨颈BMD平均数标准差为0.10（0.02-0.18；I2=0%）g/cm2,TC vs. CC为0.06（-0.04至-0.17；I2=17%）g/cm2。腰椎或全髋关节骨密度与对照组比较差异无显著性。

由此可见，丹麦人群的遗传性终生乳糖酶耐受的高牛奶摄入量与髋部骨折无关。荟萃分析还表明，乳糖酶持续性与骨折风险无关。基因乳糖酶持续性与股骨颈骨密度增高有关，而与腰椎或全髋关节BMD无关。

原始出处：

Helle KM Bergholdt, Lactase persistence, milk intake, hip fracture, and bone mineral density: A study of 97,811 Danish individuals and a meta-analysis.J INTERN MED. 2018. http://onlinelibrary.wiley.com/doi/10.1111/joim.12753/full

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    2018-12-21 spoonycyy

    #牛奶摄入量#

    0

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    2018-03-18 liuyg0228

    #持续性#

    0

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    2018-08-19 41514487@qq.com

    #乳糖酶持续#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-09-18 lmm397

    #摄入量#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-04-15 121f3903m94暂无昵称

    好

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-04-14 121f3903m94暂无昵称

    啊

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-04-06 121f3903m94暂无昵称

    嗯

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-04-05 121f3903m94暂无昵称

    啊

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-04-01 121f3903m94暂无昵称

    好的

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1797993, encodeId=00e81e97993c1, content=<a href='/topic/show?id=f1e06e75522' target=_blank style='color:#2F92EE;'>#牛奶摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67755, encryptionId=f1e06e75522, topicName=牛奶摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Dec 21 02:12:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922571, encodeId=4d0a19225e126, content=<a href='/topic/show?id=3f3156324ff' target=_blank style='color:#2F92EE;'>#持续性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56324, encryptionId=3f3156324ff, topicName=持续性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Sun Mar 18 12:12:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030256, encodeId=e178203025649, content=<a href='/topic/show?id=f1f1236e28a' target=_blank style='color:#2F92EE;'>#乳糖酶持续#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23672, encryptionId=f1f1236e28a, topicName=乳糖酶持续)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sun Aug 19 13:12:00 CST 2018, time=2018-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860623, encodeId=1dca1860623c1, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Sep 18 03:12:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306029, encodeId=e85130602921, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 15 13:11:02 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305679, encodeId=a1eb3056e937, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Apr 14 09:39:38 CST 2018, time=2018-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303121, encodeId=b1b0303121d9, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Fri Apr 06 00:20:20 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302922, encodeId=a83530292204, content=啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Thu Apr 05 07:54:40 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301738, encodeId=7d1d301e3849, content=好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sun Apr 01 10:34:57 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301462, encodeId=79c4301462ab, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5972294778, createdName=121f3903m94暂无昵称, createdTime=Sat Mar 31 10:36:29 CST 2018, time=2018-03-31, status=1, ipAttribution=)]
    2018-03-31 121f3903m94暂无昵称

    谢谢分享

    0

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