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Eur J Pediatr:肺音分析监测急性支气管炎患儿夜间咳嗽和喘息的时间过程

2020-06-29 MedSci原创 MedSci原创

咳嗽和喘息是急性支气管炎的主要症状。迄今为止,对呼吸道症状的评价仅限于问卷调查等主观方法。本研究旨在客观地确定急性支气管炎患儿咳嗽和喘息的时间过程。

咳嗽和喘息是急性支气管炎的主要症状。迄今为止,对呼吸道症状的评价仅限于问卷调查等主观方法。本研究旨在客观地确定急性支气管炎患儿咳嗽和喘息的时间过程。

 

夜间咳嗽对家长生活质量的影响作为次要结果进行评估。在36名儿童(2-8岁)中,通过自动肺音监测记录了3个夜晚的夜间咳嗽和喘息频率。此外,家长还完成了症状日志,即支气管炎严重程度评分(BSS),以及家长代理儿童急性咳嗽特异性生活质量问卷(PAC-QoL)。

 

结果显示,在第一夜,患者有34.4±52.3(平均±SD)次咳嗽,在第5夜(13.5±26.5;P<0.001)和第9夜(12.8±28.1;P<0.001)显著减少。22名患者伴有喘息,在观察期内也有所下降。所有主观参数(BSS、咳嗽日志和PAC-QoL)均与客观评估的咳嗽参数显著相关。

 

总之,该研究结果表明,长期记录咳嗽和喘息为客观评价急性支气管炎患儿呼吸道症状的时间过程提供了有用的机会。为了评估药物治疗对夜间支气管炎症状的潜在影响,今后需要在更多同质患者群体中进行研究。

 

原始出处:

 

Ulrich KoehlerOlaf Hildebrandt, et al., Time Course of Nocturnal Cough and Wheezing in Children With Acute Bronchitis Monitored by Lung Sound Analysis. Eur J Pediatr. 2019 Sep;178(9):1385-1394.

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    2021-01-31 feather89
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