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Diabetes Care:严重低血糖不增加1型糖尿病心血管风险

2012-06-05 佚名 糖尿病手机报第14期

  欧洲一项EURODIAB前瞻性并发症研究结果提示,在1型糖尿病患者中,严重低血糖并不增加心血管疾病(CVD)风险。《糖尿病护理》(Diabetes Care)2012年5月14日在线刊登。   该研究纳入2181例1型糖尿病患者,调查严重低血糖发生情况并评估随访7.3年期间CVD发病情况。其中531例患者被纳入巢式病例对照研究,分为并发症组(363例)和无并发症的对照组(168例),接受炎症

  欧洲一项EURODIAB前瞻性并发症研究结果提示,在1型糖尿病患者中,严重低血糖并不增加心血管疾病(CVD)风险。《糖尿病护理》(Diabetes Care)2012年5月14日在线刊登。

  该研究纳入2181例1型糖尿病患者,调查严重低血糖发生情况并评估随访7.3年期间CVD发病情况。其中531例患者被纳入巢式病例对照研究,分为并发症组(363例)和无并发症的对照组(168例),接受炎症、应激反应和内皮损伤标志物检测。结果为,随访期间,176例患者发生CVD。Logistic回归分析表明,基线时严重低血糖发作与CVD发病率无关,1~2次发作的校正比值比(OR)为0.78[95%可信区间(CI)0.55~1.37],≥3次的校正OR为1.09(95%CI为0.68~1.75)。内皮损伤和炎症标志物水平与低血糖发生率无关。



    

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    2013-02-08 仁医06
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