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Hypertension:收缩压控制良好降高血压患者新发房颤风险

2015-07-02 小田 译 医学论坛网

既往研究已明确了高血压和心房颤动(以下简称房颤)的相关性;的确,即使是正常收缩压(SBP)高值水平也是房颤发生的长期预测因素。这些研究结果提示,采取更为积极的血压控制可能减少新发房颤风险。但实现较低水平的SBP是否与房颤发生率较低有关尚不清楚。因此,欧洲学者们对上述问题进行了研究。 研究纳入了8831例心电图证明左心室肥大但无房颤病史的高血压患者,

既往研究已明确了高血压和心房颤动(以下简称房颤)的相关性;的确,即使是正常收缩压(SBP)高值水平也是房颤发生的长期预测因素。这些研究结果提示,采取更为积极的血压控制可能减少新发房颤风险。但实现较低水平的SBP是否与房颤发生率较低有关尚不清楚。因此,欧洲学者们对上述问题进行了研究。

研究纳入了8831例心电图证明左心室肥大但无房颤病史的高血压患者,患者基线心电图显示为窦性心律,随机分为基于氯沙坦或阿替洛尔的治疗组,对其新发房颤风险进行评估。对SBP ≤130 mm Hg、SBP 131~141 mm Hg和≥142 mm Hg的患者进行比较。

结果显示,在随访的4.6±1.1年中,701例患者被诊断为新发房颤(7.9%)。在多变量Cox分析中,与治疗期间SBP ≥142 mm Hg相比,SBP ≤130 mm Hg、SBP 131~141 mm Hg作为时间变量分别与40%和24%的新发房颤风险较低有关。

该研究表明,实现SBP ≤130 mm Hg与心电图证实左心室肥厚高血压患者的新发房颤风险较低有关。需确定无房颤高血压患者SBP目标值的进一步研究可以减少高危人群新发房颤的负担。

相关研究论文6月8日在线发表于《高血压》(Hypertesion)杂志。

原始出处:

Okin PM1, Hille DA2, Larstorp AC2, Wachtell K2, Kjeldsen SE2, Dahlöf B2, Devereux RB2.Effect of Lower On-Treatment Systolic Blood Pressure on the Risk of Atrial Fibrillation in Hypertensive Patients.Hypertension.June 8, 2015. pii: HYPERTENSIONAHA.115.05728. 

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    2015-07-12 feather89
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createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481366, encodeId=7f0c148136682, content=<a href='/topic/show?id=ce0258131ff' target=_blank style='color:#2F92EE;'>#新发房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58131, encryptionId=ce0258131ff, topicName=新发房颤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=788d7780866, createdName=若水125, createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501059, encodeId=45f7150105948, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531994, encodeId=7b961531994b2, content=<a href='/topic/show?id=b0885428229' target=_blank style='color:#2F92EE;'>#房颤风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54282, encryptionId=b0885428229, topicName=房颤风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ea612304943, createdName=whmdzju, createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30225, encodeId=b9d23022514, content=不错的, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Jul 02 12:58:00 CST 2015, time=2015-07-02, status=1, ipAttribution=)]
    2015-07-18 aa6081

    进一步学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2038513, encodeId=fea320385131a, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Thu Oct 29 09:55:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725864, encodeId=cb741e2586421, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdName=aa6081, createdTime=Sat Jul 18 00:35:00 CST 2015, time=2015-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30556, encodeId=6da330556f7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sat Jul 04 15:16:00 CST 2015, time=2015-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448142, encodeId=a39f14481429f, content=<a href='/topic/show?id=5a9c102681f2' target=_blank style='color:#2F92EE;'>#高血压患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102681, encryptionId=5a9c102681f2, topicName=高血压患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4665409655, createdName=维他命, createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481366, encodeId=7f0c148136682, content=<a href='/topic/show?id=ce0258131ff' target=_blank style='color:#2F92EE;'>#新发房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58131, encryptionId=ce0258131ff, topicName=新发房颤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=788d7780866, createdName=若水125, createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501059, encodeId=45f7150105948, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, 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attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Jul 02 12:58:00 CST 2015, time=2015-07-02, status=1, ipAttribution=)]
    2015-07-04 huaxipanxing

    看看

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2038513, encodeId=fea320385131a, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Thu Oct 29 09:55:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725864, encodeId=cb741e2586421, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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  7. [GetPortalCommentsPageByObjectIdResponse(id=2038513, encodeId=fea320385131a, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Thu Oct 29 09:55:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725864, encodeId=cb741e2586421, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481366, encodeId=7f0c148136682, content=<a href='/topic/show?id=ce0258131ff' target=_blank style='color:#2F92EE;'>#新发房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58131, encryptionId=ce0258131ff, topicName=新发房颤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=788d7780866, createdName=若水125, createdTime=Fri Jul 03 23:55:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501059, encodeId=45f7150105948, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, 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  8. 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  9. 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    2015-07-02 owlhealth

    不错的

    0

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