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糖尿病人群基线高敏C反应蛋白3.0mg/L新发心脑血管事件风险高

2012-08-07 晓静 摘编 医学论坛网

  河北联合大学附属开滦医院与河北遵化市人民医院和唐山市第三医院联合研究发现,基线高敏C反应蛋白(hsC-RP)>3.0mg/L增加无高血压病史的糖尿病人群新发心脑血管事件的风险。 相关论文发表于2012年第6期《中国糖尿病杂志》。   研究者们采用前瞻性队列研究方法,以参加健康体检的101510名开滦集团职工中FPG≥7.0mmol/L或已确诊为糖尿病,正在使用降糖药物的297

  河北联合大学附属开滦医院与河北遵化市人民医院和唐山市第三医院联合研究发现,基线高敏C反应蛋白(hsC-RP)>3.0mg/L增加无高血压病史的糖尿病人群新发心脑血管事件的风险。 相关论文发表于2012年第6期《中国糖尿病杂志》。

  研究者们采用前瞻性队列研究方法,以参加健康体检的101510名开滦集团职工中FPG≥7.0mmol/L或已确诊为糖尿病,正在使用降糖药物的2973例糖尿病患者作为观察队列,平均随访(47.26±5.38)个月。

  结果显示,基线hsC-RP水平增高,心脑血管事件发生率、死亡率、全因死亡率增高(P<0.05)。Cox风险模型表明,hsC-RP>3.0mg/L者发生心脑血管事件、心脑血管死亡、全因死亡的风险分别是hsC-RP≤3.0mg/L者的1.63倍(95%CI:1.03~2.57)、2.62倍(95%CI:1.12~6.12)和1.73倍(95%CI:1.06~2.84)。

 

    

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