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Pediatrics:儿童医院能提供镰状细胞病并发症更佳护理

2013-11-05 佚名 睿医资讯

一项回顾性研究提示,具有镰状细胞病(SCD)和急性胸痛综合征的青少年及年轻成人患者,在综合医院得到的护理与在儿童医院所得到的护理不尽相同。这项研究显示,在综合医院接受治疗的患者,气管插管的比率更高,且住院时间更长,但患者的30天再入院率并无差异。 研究者发现,急性胸痛综合征是SCD患者的主要死因,而血管闭塞性疼痛是导致患者住院的最常见原因。 此外,研究人员还注意

一项回顾性研究提示,具有镰状细胞病(SCD)和急性胸痛综合征的青少年及年轻成人患者,在综合医院得到的护理与在儿童医院所得到的护理不尽相同。这项研究显示,在综合医院接受治疗的患者,气管插管的比率更高,且住院时间更长,但患者的30天再入院率并无差异。

研究者发现,急性胸痛综合征是SCD患者的主要死因,而血管闭塞性疼痛是导致患者住院的最常见原因。

此外,研究人员还注意到,美国多数SCD患儿在大规模学术性儿童医院的SCD中心接受随访,但这些患儿的年龄已经超出这类中心的年龄限制,医保很可能不能覆盖这部分患者。这些患者大多难以找到合适的SCD治疗机构,导致治疗中断。

宾夕法尼亚州费城儿童医院的Sophia Jan博士及其同事回顾了1378例16-25岁的SCD患者数据,其中2178例患者于2007-2009年间因急性胸痛综合征入住儿童医院,244例进入综合性医院接受治疗。

在这些患者中,14例死亡,45%的患者接受了气管插管处理。

与在儿童医院接受治疗的患者相比,综合性医院的患者死亡例数(13例)和气管插管的比例(48% vs 24%,P=0.045)更高。此外,综合性医院的患者住院的时间(LOS)更长(7.6天 vs 6.2天)。

综合性医院的气管插管比率和LOS较长“可能提示了儿童医院具有特定的工作机制和专业技术,使得患者预后较综合性医院患者而有所改善。”

在这项研究中,接受综合性医院治疗的患者慢性疾病的状况更复杂,且之前接受ICU治疗的次数更多。

近半数因急性胸痛综合征入院的患者接受了单纯输血治疗(42%)、交换输血治疗(2%)或两种疗法联合应用(1%)。在输血治疗的方式或30天再入院率方面,不同类型的医院并无明显不同。

原文出处:

Jan S, Slap G, Smith-Whitley K, Dai D, Keren R, Rubin DM.Association of Hospital and Provider Types on Sickle Cell Disease Outcomes.Pediatrics. 2013 Oct 28.

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    2014-03-05 丁鹏鹏
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    2014-04-25 feather89
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    2014-04-09 hbwxf
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1757584, encodeId=8f691e57584c2, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Wed Mar 05 10:38:00 CST 2014, time=2014-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725545, encodeId=27611e25545a8, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Apr 25 03:38:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958381, encodeId=0733195838170, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Wed Apr 09 21:38:00 CST 2014, time=2014-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636758, encodeId=a4211636e582c, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Aug 29 05:38:00 CST 2014, time=2014-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392671, encodeId=e8ca13926e1d5, content=<a href='/topic/show?id=d0c22821069' target=_blank style='color:#2F92EE;'>#儿童医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28210, encryptionId=d0c22821069, topicName=儿童医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Thu Nov 07 00:38:00 CST 2013, time=2013-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615460, encodeId=be2b1615460d3, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Thu Nov 07 00:38:00 CST 2013, time=2013-11-07, status=1, ipAttribution=)]
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