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Chest:支气管扩张症严重程度是血管疾病的危险因素

2016-10-24 MedSci MedSci原创

背景:慢性阻塞性肺疾病和肺炎与血管疾病的相关性的研究有所增加,但支气管扩张症与血管疾病之间的关系的研究较少。方法:记录2013年5月到2014年9月间,英国爱丁堡NHS Lothian支气管扩张症患者,对其进行回顾性的研究。研究评估血管性疾病(缺血性心脏病、脑血管病、外周血管疾病和房颤)的患病率。使用多变量模型识别诊断为支气管扩张症的患者,患血管疾病的独立危险因素。结果:这项研究包括400例患者。

背景:慢性阻塞性肺疾病和肺炎与血管疾病的相关性的研究有所增加,但支气管扩张症与血管疾病之间的关系的研究较少。

方法:记录2013年5月到2014年9月间,英国爱丁堡NHS Lothian支气管扩张症患者,对其进行回顾性的研究。研究评估血管性疾病(缺血性心脏病、脑血管病、外周血管疾病和房颤)的患病率。使用多变量模型识别诊断为支气管扩张症的患者,患血管疾病的独立危险因素。

结果:这项研究包括400例患者。44例(11%)在诊断支气管扩张症之前存在血管疾病,45例(11%)患者在诊断支气管扩张症后平均9.4 (95%CI[6.0-12.8])年,血管疾病发生。诊断支气管扩张症后发生血管疾病的独立相关因素:男性、高血压、长期他汀类药物治疗,中度或重度的支气管扩张。

结论:总之,诊断为支气管扩张症之后,支气管扩张症的严重程度与血管疾病发展独立相关。需要进行进一步研究以确定支气管扩张症患者的一级和二级预防。

原始出处:

Evans IE, Bedi P,et al. Bronchiectasis severity is an independent risk factor for vascular disease in a Bronchiectasis Cohort. Chest. 2016 Oct 6.


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    2017-07-09 Smile2680
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    2017-06-30 lsj637
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    2016-10-25 qixiaotong123

    心肺相互作用

    0

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