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SLEEP:若患有精神疾病,则更易出现睡眠问题

2015-12-07 QQduhq 译 MedSci原创

目的 该研究旨在使用全球数据库,评估民众出现睡眠问题的发生率与其精神疾病症状之间的关系。 方法 该研究是以社区为基础的横断面研究。研究人员使用WHS,对2002-2004年间的相关数据进行分析,共涉及70个国家。参与人员共261547位,他们来自56个国家,平均年龄超过18岁。结果评估参与者过去1年内是否有精神疾病表现则根据复合型国际诊断交谈表中的四大内容。同时评估参与者最近30天内是否存在睡眠障

目的:该研究旨在使用全球数据库,评估民众出现睡眠问题的发生率与其精神疾病症状之间的关系。

 
方法:该研究是以社区为基础的横断面研究。研究人员使用WHS,对2002-2004年间的相关数据进行分析,共涉及70个国家。参与人员共261547位,他们来自56个国家,平均年龄超过18岁。

结果:评估参与者过去1年内是否有精神疾病表现则根据复合型国际诊断交谈表中的四大内容。同时评估参与者最近30天内是否存在睡眠障碍或严重睡眠问题。研究人员采用多变量逻辑回归分析探究二者之间的关系。结果表明,出现睡眠问题患者比例平均为7.6%,范围从1.6%(中国)到18.6%(摩洛哥)。若一个国家出现精神症状的人数较多,则他们出现睡眠问题的发生率也较高。对人口因素、饮酒、吸烟、慢性疾病等因素进行调整之后,研究人员发现,精神疾病(至少1个)导致民众出现睡眠问题的优势比(OR)为2.41(95%CI:2.18-2.65)。若调整焦虑和抑郁情绪等因素后,优势比为1.59(95%CI:1.40 -1.81)。

结论:通过使用全球性数据,研究人员得出结论:精神疾病对患者出现睡眠问题有直接影响作用。这些结果相当具有临床意义,并且对未来深入探究精神疾病与睡眠问题之间的因果联系具有十分重要的意义。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1940954, encodeId=31ff1940954b5, content=<a href='/topic/show?id=297ae304202' target=_blank style='color:#2F92EE;'>#睡眠问题#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73042, encryptionId=297ae304202, topicName=睡眠问题)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Aug 01 05:02:00 CST 2016, time=2016-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49677, encodeId=90a3496e791, content=好学习很值得, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 21:05:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48828, encodeId=9b96488281f, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:19:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48829, encodeId=16284882989, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:19:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1344926, encodeId=cfdf13449267b, content=<a href='/topic/show?id=cf721640495' target=_blank style='color:#2F92EE;'>#SLE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16404, encryptionId=cf721640495, topicName=SLE)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/kbRUeosenzlejlNGWXdWjSYhBKL1QYGQwfehJOkMXHiavh5wl7pKeju5Kcxdvr50ic6FWML3x6NMCxhG1bOaVjyA/132, createdBy=20872500216, createdName=ms4657536712156177, createdTime=Wed Dec 09 06:02:00 CST 2015, time=2015-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45248, encodeId=737145248f3, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Tue Dec 08 20:14:00 CST 2015, time=2015-12-08, status=1, ipAttribution=)]
    2015-12-27 忠诚向上

    好学习很值得

    0

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    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

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    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

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    2015-12-08 三三五五

    有意思

    0

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威斯康星大学麦迪逊分校的一项研究发现,焦虑是可以遗传的。研究人员扫描了年轻小猴子在轻微压力事件下的大脑反应,并将之与其父母、亲戚的结果作对比。结果发现,在更为焦虑的猴宝宝中,大脑的三个不同部位的反应模式与其父母一模一样。这些焦虑所致的大脑反应似乎是遗传的,而这仅仅是一个开头罢了——大量精神疾病都有强烈的基因影响。 寻找特定精神疾病的遗传性是很有意义的。首先,这可以提醒那些患有精神疾病的人认真考虑

“南京宝马案”类的精神疾病你知道多少?

新闻背景:2015年6月20日,江苏省南京市区发生一起宝马车与多车相撞的交通事故,造成2人死亡,1人受伤,多车受损。近日,南京警方通报“6·20”宝马车祸惨案最近情况:经医学鉴定,肇事司机作案时患急性短暂性精神障碍,有限制刑事责任能力。该事件引发网友争议。 在北京回龙观医院,医生指导轻度精神障碍患者通过制作陶艺进行辅助治疗。 一脚油门,近200公里时速,撞碎一辆马自达轿

Am J Psychiat:有精神疾病的孕妇真的不能服用抗抑郁药物吗?不是这样的

根据哥伦比亚大学医学中心的哥伦比亚大学梅尔曼学院公共卫生学院和纽约州立精神病研究所的研究员介绍,通常用抗忧郁药治疗产妇精神障碍后可引发风险较低的某些妊娠并发症,包括早产和通过剖腹产分娩。然而,这些药物 ——选择性血清素再吸收抑制剂(SSRIs)—— 可导致新生儿问题的风险增加。研究结果在线发表在美国精神病学杂志上。“据我们所知,在怀孕期间服用抗抑郁药风险较低的早产之间的关联是一个新的发现,”艾伦·

Nature:诺奖得主新研究——神经递质快速传递的“奥秘”

近日,来自美国斯坦福大学的研究人员在著名国际学术期刊nature上发表了一项最新研究进展,他们对大脑如何在神经细胞之间快速传递信号进行了前所未有的细节揭露。他们绘制了神经细胞上调控神经递质释放的一种重要蛋白复合体的3D原子结构,这能够帮助我们了解神经细胞之间如何在千分之一秒内完成信号传递,对于脑神经疾病治疗药物的开发具有重要意义。   研究人员指出,这是一项非常重要也非常令人兴奋的

科技奖|华西医院精神疾病研究获奖

21世纪是脑科学时代,美欧相继启动了与人类基因组计划相媲美的脑科学计划,其目的是阐明人类大脑工作机制,为揭示重大神经精神疾病的脑机制进而研发新型诊治方法打下理论基础。如何准确无创的测量脑结构和功能成为揭示脑活动机制的核心问题。医学磁共振成像属于新型交叉学科领域,能活体无创评估脑结构、功能等信息,为揭示脑工作机制提供了新的手段和研究方向。龚启勇教授项目组在相关国家重大课题的连续资助下,经过10年的努

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