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Am J Obstet Gynecol:经阴道全子宫切除术中行预防性输卵管切除术的可行性研究。

2017-07-20 MedSci MedSci原创

探讨经阴道子宫切除术中行双侧输卵管切除的可行性。评估影响成功切除输卵管的因素,以及切除输卵管对手术时间、失血量、手术并发症和更年期综合征的影响。

背景:美国妇产科学会推荐外科医生和患者一起讨论在未行卵巢切除术的女性中,切除子宫的同时切除输卵管预防卵巢癌的潜在好处,导致子宫切除术中行输卵管切除术的概率增加。输卵管切除术最常见于腹腔镜检查术,在经阴道子宫切除术中最少见。

目的:本研究的主要目的是探讨经阴道子宫切除术中行双侧输卵管切除的可行性。此外还评估影响成功切除输卵管的因素,以及切除输卵管对手术时间、失血量、手术并发症和更年期综合征的影响。
设计:研究人员进行了一个多中心合作、前瞻性研究,招募计划行经阴道子宫及双侧输卵管切除术的患者。输卵管切除术中的所见、手术时间及失血量的相关数据均记录在册。患者在术前和术后随访时均填写更年期评定量表。运用各种统计学分析处理数据。

结果:共招募了77位患者,74位(96%)同意,69位(93%)有完整可供分析的数据。平均年龄51岁。中位BMI是29.1kg/m2;中位顺娩次数是2次,41%的患者已绝经。子宫切除术的手术指征有子宫脱垂(78%),重度子宫异常出血(20%)和子宫肌瘤(11%)。除去更改手术途径,64位患者中有52位(81%)成功行经阴道输卵管切除术。行双侧输卵管切除术的平均时间是11min(±5.6),额外失血量6ml(±16.3)。有8例出现手术并发症:3例出血>500ml,5例改变手术方式,但都不是因为行输卵管切除术。子宫平均重量102g,所有输卵管病理报告中未见恶性。17位计划行双侧输卵管切除的患者未能完成,其中7位行单侧输卵管切除术。未能切除输卵管的原因:输卵管位置高(8例)、因病理改变手术方式(4例)、肠粘连或侧壁粘连(3例)、输卵管缺如(1例)和卵巢粘连(1例)。既往附件区做过手术和子宫肌瘤是成功切除双侧输卵管的独立影响因素。输卵管切除术后更年期平均评分升高。

结论:经阴道行输卵管切除术在多数行经阴道子宫切除术的患者中是可行的,增加手术时间11min、失血量6ml。此外,应该告知既往做过附件区手术和子宫肌瘤的患者不能成功经阴道切除输卵管的可能性。

原始出处:

Danielle D.Aneosh,Rachel High,et al.Feasibility of Prophylactic Salpingectomy During Vaginal Hysterectomy.Am J Obstet gynecol.July 19,2017.http://dx.doi.org/10.1016/j.ajog.2017.07.017.

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  4. 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  5. 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  6. 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  7. 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time=2017-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2034774, encodeId=bb912034e7437, content=<a href='/topic/show?id=69c910030635' target=_blank style='color:#2F92EE;'>#预防性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100306, encryptionId=69c910030635, topicName=预防性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Thu Feb 08 05:48:00 CST 2018, time=2018-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043999, encodeId=14c0204399933, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, 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  8. [GetPortalCommentsPageByObjectIdResponse(id=1709260, encodeId=0ea11e0926080, content=<a href='/topic/show?id=5b354516591' target=_blank style='color:#2F92EE;'>#子宫切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45165, encryptionId=5b354516591, topicName=子宫切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=982231632710, createdName=12498aa2m72(暂无昵称), createdTime=Sun Oct 22 06:48:00 CST 2017, time=2017-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876914, encodeId=116218e69145c, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, 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time=2017-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2034774, encodeId=bb912034e7437, content=<a href='/topic/show?id=69c910030635' target=_blank style='color:#2F92EE;'>#预防性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100306, encryptionId=69c910030635, topicName=预防性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Thu Feb 08 05:48:00 CST 2018, time=2018-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043999, encodeId=14c0204399933, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1709260, encodeId=0ea11e0926080, content=<a href='/topic/show?id=5b354516591' target=_blank style='color:#2F92EE;'>#子宫切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45165, encryptionId=5b354516591, topicName=子宫切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=982231632710, createdName=12498aa2m72(暂无昵称), createdTime=Sun Oct 22 06:48:00 CST 2017, time=2017-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876914, encodeId=116218e69145c, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, 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  10. 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    2017-09-03 yhy100200

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