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多学科综合治疗是结直肠癌重要治疗模式

2012-11-16 Jane摘编 医学论坛网

     中山大学附属第六医院汪建平教授评述了中国结直肠癌治疗现状—进步与局限并存,从我国结直肠癌生存率、治疗手段进步以及发展局限性进行了深刻地剖析。该论文发表在2012年第10期《中华胃肠外科杂志》。   据WHO2008年公布的数据显示,我国结直肠癌5年生存率仅为32%,低于北美国家。分析原因主要有两个:一是我国早期结直肠癌患者比例低;二是我国医疗水平不均衡性。   我国结直肠癌诊治取得

  汪建平

  中山大学附属第六医院汪建平教授评述了中国结直肠癌治疗现状—进步与局限并存,从我国结直肠癌生存率、治疗手段进步以及发展局限性进行了深刻地剖析。该论文发表在2012年第10期《中华胃肠外科杂志》。

  据WHO2008年公布的数据显示,我国结直肠癌5年生存率仅为32%,低于北美国家。分析原因主要有两个:一是我国早期结直肠癌患者比例低;二是我国医疗水平不均衡性。

  我国结直肠癌诊治取得了一定的进步,1)多学科综合治疗(MDT)观念逐渐深入,MDT是结直肠癌以及其他种类治疗的重要模式。2)新辅助放化疗理念逐步推广,新辅助放化疗目前主要用于中低位直肠癌,是指在手术切除前给予的化疗和局部放疗,目的是提高手术切除率、提高保肛率和延长患者无病生存期。3)腹腔镜微创手术愈来愈普及;4)结直肠癌肝转移的治疗策略有新转变;5)个体化治疗紧跟国际方向。

  汪教授指出,尽管结直肠癌的治疗已经取得了一些进步,但仍存在局限性,1)缺乏基于中国人群的大宗临床研究,现开展的FOWARC研究是针对局部进展型直肠癌的前瞻性多中心随机对照研究。2)直肠癌的放疗不普及;3)标准的手术方式在中国仍未普及,尤其是关于是否保肛理念,2010年卫生部出台《结直肠癌诊疗规范》要求,肠壁远切缘需距离肿瘤大于或等于2cm,如远切缘为1~2cm,需术中冰冻病理检查证实切缘阴性。这样既考虑了手术的根治性和安全性,也避免了滥用保肛手术;4)规范化虽得到国家重视但仍任重而道远;5)专科化诊治进展缓慢。



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  2012年10月19日-24日在内华达州拉斯维加斯威尼斯人度假村酒店召开的美国胃肠病学会(ACG)2012年科学会议和研究生课程的焦点将是新的胃肠病学研究、消化疾病的治疗以及临床实践管理。这次盛典预计迎来超过5000名胃肠病学家,已经吸引学者提交了创新纪录的2007篇摘要,包括1659篇壁报和67篇口头报告。   “我认为美国胃肠病学会的整体科学水平越来越高,所以吸引了很多人。” 美国胃肠病

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