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Stroke:康复治疗对缺血性脑卒中患者预后的影响

2017-01-24 MedSci MedSci原创

缺血性脑卒中是指由于脑的供血动脉(颈动脉和椎动脉)狭窄或闭塞、脑供血不足导致的脑组织坏死的总称。卒中患者常见的障碍为运动障碍 (包括肢体痉挛状态)、感觉障碍、语言/言语功能障碍 (失语症和/或构音障碍)、吞咽障碍、认知障碍、视觉障碍和卒中后抑郁。其中运动障碍最为常见。虽然卒中的康复需求随时间而极大地增加,但目前只有部分有效的神经康复措施可以使用,而一些有希望的治疗还处于研究阶段。最新一期的stro

缺血性脑卒中是指由于脑的供血动脉(颈动脉和椎动脉)狭窄或闭塞、脑供血不足导致的脑组织坏死的总称。卒中患者常见的障碍为运动障碍 (包括肢体痉挛状态)、感觉障碍、语言/言语功能障碍 (失语症和/或构音障碍)、吞咽障碍、认知障碍、视觉障碍和卒中后抑郁。其中运动障碍最为常见。
虽然卒中的康复需求随时间而极大地增加,但目前只有部分有效的神经康复措施可以使用,而一些有希望的治疗还处于研究阶段。

最新一期的stroke上的一项研究对缺血性卒中患者来讲,康复治疗的强度和时间对其日常生活活动(activities of daily living,ADL)的影响。

研究人员使用日本诊断程序联合住院患者数据库对2012.4-2014.3的100 719例接受康复治疗的缺血性脑卒中住院患者进行了回顾性分析。早期康复被定义为入院后3天内开始的康复治疗。平均每天康复强度通过住院期间康复的总单位除以总的住院天数计算。多重填充的多变量Logistic回归分析和工具变量分析被用来评估早期强化康复与ADL评分提高之间的联系。

早期强化康复组,ADL分数提高的患者比例更高。多变量Logistic回归分析显示,在日常生活显着改善,早期康复(OR:1.08;95%置信区间:1.04-1.13;P<0.01)和强度>5.0单位/天的强化康复(OR:1.87;95%置信区间:1.69-2.07;P<0.01)显著提高患者ADL。工具变量分析表明,ADL改善者比例的增加与早期康复(危险差RD:2.8%;95%置信区间:2.0-3.4 %;P<0.001)和强化康复(RD:5.6%;95%置信区间:4.6-6.6 %;P<0.001)相关。

本实验结果提示,缺血性脑卒中患者住院期间早期开始强化康复有助于改善其日常生活活动。

原始出处:

Yagi M1, Yasunaga H,et al.Impact of Rehabilitation on Outcomes in Patients With Ischemic Stroke: A Nationwide Retrospective Cohort Study in Japan.Stroke. 2017 Jan 20. pii: STROKEAHA.116.015147. doi: 10.1161/STROKEAHA.116.015147.

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  4. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Mon Mar 27 21:20:00 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1691891, encodeId=a6161691891b3, content=<a href='/topic/show?id=a450530853c' target=_blank style='color:#2F92EE;'>#患者预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53085, encryptionId=a450530853c, topicName=患者预后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f4729287700, createdName=bnurmamat, createdTime=Fri Jul 28 20:20:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), 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createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
  5. 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createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
  6. 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createdName=186****0580(小山羊), createdTime=Thu Jan 26 10:22:02 CST 2017, time=2017-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172546, encodeId=398f1e25468a, content=不错不错,多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Jan 25 14:40:10 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172528, encodeId=211e1e252843, content=脑卒中的预后和康复有很大关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c2ab1385675, createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
    2017-02-11 虈亣靌

    好文,值得点赞,值得拥有,值得收藏!

    0

  7. 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createdBy=66ec123, createdName=guihongzh, createdTime=Tue Oct 24 02:20:00 CST 2017, time=2017-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1807031, encodeId=0f70180e031cf, content=<a href='/topic/show?id=245de9378aa' target=_blank style='color:#2F92EE;'>#缺血性脑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79378, encryptionId=245de9378aa, topicName=缺血性脑)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLGtr9t89oicQdQSIeKmOQic1weIWfibJ7H24XnT8ic9wiaUMTnXByenuwicOj8Jib42ibHXNptnuiaKthhiaVw/132, createdBy=ac342500190, createdName=ms7524819409032184, createdTime=Mon Oct 16 00:20:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720147, encodeId=a9d31e20147c8, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Mon Mar 27 21:20:00 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1691891, encodeId=a6161691891b3, content=<a href='/topic/show?id=a450530853c' target=_blank style='color:#2F92EE;'>#患者预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53085, encryptionId=a450530853c, topicName=患者预后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f4729287700, createdName=bnurmamat, createdTime=Fri Jul 28 20:20:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175473, encodeId=9ff41e54738d, content=好文,值得点赞,值得拥有,值得收藏!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Feb 11 04:30:19 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172674, encodeId=6e711e26744f, content=学习了,分享了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Jan 26 10:22:02 CST 2017, time=2017-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172546, encodeId=398f1e25468a, content=不错不错,多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Jan 25 14:40:10 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172528, encodeId=211e1e252843, content=脑卒中的预后和康复有很大关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c2ab1385675, createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
    2017-01-26 186****0580(小山羊)

    学习了,分享了。

    0

  8. 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createdBy=66ec123, createdName=guihongzh, createdTime=Tue Oct 24 02:20:00 CST 2017, time=2017-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1807031, encodeId=0f70180e031cf, content=<a href='/topic/show?id=245de9378aa' target=_blank style='color:#2F92EE;'>#缺血性脑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79378, encryptionId=245de9378aa, topicName=缺血性脑)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLGtr9t89oicQdQSIeKmOQic1weIWfibJ7H24XnT8ic9wiaUMTnXByenuwicOj8Jib42ibHXNptnuiaKthhiaVw/132, createdBy=ac342500190, createdName=ms7524819409032184, createdTime=Mon Oct 16 00:20:00 CST 2017, time=2017-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720147, encodeId=a9d31e20147c8, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, 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createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
    2017-01-25 1e10c84am36(暂无匿称)

    不错不错,多读受益

    0

  9. 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createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
    2017-01-25 hhuanjie

    脑卒中的预后和康复有很大关系

    0

  10. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Mon Mar 27 21:20:00 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1691891, encodeId=a6161691891b3, content=<a href='/topic/show?id=a450530853c' target=_blank style='color:#2F92EE;'>#患者预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53085, encryptionId=a450530853c, topicName=患者预后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f4729287700, createdName=bnurmamat, createdTime=Fri Jul 28 20:20:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175473, encodeId=9ff41e54738d, content=好文,值得点赞,值得拥有,值得收藏!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Feb 11 04:30:19 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172674, encodeId=6e711e26744f, content=学习了,分享了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Jan 26 10:22:02 CST 2017, time=2017-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172546, encodeId=398f1e25468a, content=不错不错,多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Jan 25 14:40:10 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172528, encodeId=211e1e252843, content=脑卒中的预后和康复有很大关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c2ab1385675, createdName=hhuanjie, createdTime=Wed Jan 25 12:04:37 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172522, encodeId=52911e2522bc, content=这很有用,康复治疗里可以加入传统医学内容。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Jan 25 10:25:43 CST 2017, time=2017-01-25, status=1, ipAttribution=)]
    2017-01-25 smartxiuxiu

    这很有用,康复治疗里可以加入传统医学内容。

    0

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